DOI: http://dx.doi.org/10.18203/2349-3933.ijam20181093

Inferior vena cava thrombosis as a complication of Crohn’s disease

Parthiban G.

Abstract


Twenty-nine years old male, a case of Crohn's disease diagnosed by histopathology 5 years back, when he developed a perforative peritonitis. Resection and anastomosis was done, and he was started on Mesalamine therapy. Patient stopped the drug 8 months back and presented with cough for 1-month duration. HRCT chest showed IVC thrombosis. CECT abdomen showed intrahepatic extension of thrombus with active colitis and absent left testicle in scrotum with no intra-abdominal testicle. Coagulation parameters were normal. Colonoscopy and biopsy was done showing features of active Crohn's disease. Patient was restarted on Mesalamine and anticoagulation. Follow up imaging showed features of resolution of thrombus.


Keywords


Crohn’s disease, IVC thrombosis

Full Text:

PDF

References


Solem CA, Loftus EV, Tremaine WJ, Sandborn WJ. Venous thromboembolism in inflammatory bowel disease. Am J Gastroenterol. 2004 99(1):97-101.

Talbot RW, Heppell J, Dozois RR, Beart RW. Vascular complications of inflammatory bowel disease. Mayo Clin Proc. 1986;61(2):140-5.

Jackson LM, O’Gorman PJ, O’Connell J, Cronin CC, Cotter KP, Shanahan F. Thrombosis in inflammatory bowel disease: clinical setting, procoagulant profile and factor V Leiden. QJM Mon J Assoc Physicians. 1997;90(3):183-8.

López Morante AJ, Prieto García M, Yuguero del Moral L, Sáez-Royuela F, Martín Lorente JL, Ojeda Giménez C. Coagulation changes in inflammatory intestinal disease. Rev Clínica Esp. 1992;190(1):18-21.

Lake AM, Stauffer JQ, Stuart MJ. Hemostatic alterations in inflammatory bowel disease: response to therapy. Am J Dig Dis. 1978;23(10):897-902.

Baker WF. Thrombolytic therapy. Clin Appl Thromb Off J Int Acad Clin Appl Thromb. 2002;8(4):291-314.

Björgell O, Nilsson P, Nilsson A, Lorén I, Florén CH, Lindgärde F. Isolated internal iliac vein thrombosis. J Ultrasound Med Off J Am Inst Ultrasound Med. 1998;17(10):671-3.

Tabibian JH, Lada SJ, Tabibian N. Combined Inferior Vena Cava and Renal Vein Thromboses: Case and Synopsis of Thromboembolism in Inflammatory Bowel Disease. Medscape J Med. 2008;10(1):6.