DOI: http://dx.doi.org/10.18203/2349-3933.ijam20181086

Pattern and incidence of ventilator associated pneumonia among mechanically ventilated patients

Mukesh Dube, Shraddha Goswami, Abhishek Singh, Bhavani Mohan Raju, Pradip Dube, G. C. Bhatia

Abstract


Background: Initial empirical therapy of ventilator-associated pneumonia (VAP), which is based on organisms recovered, can be modified based on the knowledge of local microbiological data, patient characteristics, and sensitivity pattern of expected pathogens at the institution. Aim of this study was conducted to observe the regional the incidence of VAP among mechanically ventilated patients.

Methods: All the patients who conformed to the inclusion criteria of the study, and who were in the ICU settings and put on ventilatory support, underwent vigorous aseptic precautions and later on developed VAP were taken into the study.

Results: Total 374 admitted patients were needed mechanically ventilation. Among 31 developed LRTI. The Overall incidence rate of VAP was computed to be 8.2% with highest rate among patients of age group 31-50 years. The incidence rates of VAP were found highest for Acinetobacter (54.8%) with second highest mortality (47%) whereas maximum mortality (66.66%) was caused by Klebsiella, the second most common incidence of VAP. Twenty-one patients developed early VAP whereas remaining 10 subjects developed late VAP. Mortality was higher between early VAP (57.14%) compared to the late VAP cases (30%). Majority of organisms were sensitive to Cefoperazone + Sulbactum (29), Imipenem (24) and Meropenem (22).

Conclusions: Despite advances in diagnostic and treatment modalities of VAP, its management still continues to be a challenge for clinicians. The findings emerging out of this investigation will help in initial selection of antibiotics for the empiric treatment of VAP. Later on, therapy can be modified based on the knowledge of pattern and profile of VAP patients along with sensitivity pattern of expected pathogens.


Keywords


Intensive care unit, Mechanical ventilation, Ventilator-associated pneumonia

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