Comparative evaluation of topical and intravenous lignocaine for insertion of laryngeal mask airway with propofol

Saba Ahmed, Namrata Jain, Sanjay Saksena


Background: Objective of present study to determine that administration of Intravenous Lignocaine prior to propofol is as effective as topically on the posterior oropharynx for LMA insertion.

Methods: 60 patients of age group 16-45years of both sexes, ASA Grade I and II undergoing elective surgeries. Group 1: (n=30) Patients receiving Lignocaine 1.5 mg/kg IV over 30 seconds. Group 2: (n=30) Patients receiving lignocaine aerosol 40 mg topically. Conditions of LMA insertion, gagging laryngospasm ,coughing noted at time of insertion, ECG, NIBP, SPO2 and ETCO2 were recorded according to scheduled times.

Results: In Conditions of insertion, difference between groups reached significance, p<0.05. In groups at first min, rise in heart rate, fall in DSP, SBP and MAP was significant. At two and three minutes post LMA insertion these parameters change slightly but statistically not significant.

Conclusions: Topical Lignocaine 10% aerosol prior to propofol induction provides excellent conditions for LMA insertion without the use of neuromuscular blockages.


LMA Laryngeal mask airway, Topical lignocaine aerosol

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Verghese C, Mena G, Ferson DZ. Brain and Hagberg's Airway Management (Third Edition) 2013:443-65.

Brimacombe J, Berry A. Insertion of LMA-an indication for propofol? Anaesth Intensive Care. 1992 Aug;20(3):394-5.

Driver IK, Wiltshire S, Mills P, Lillywhite N, Howard-Griffin R. Midazolam co-induction and laryngeal mask insertion. Anaesthesia. 1996 Aug;51(8):782-4.

Stoneham MD, Bree SE, Sneyd JR. Facilitation of laryngeal mask insertion. Effects of lignocaine given intravenously before induction with propofol. Anaesthesia. 1995 May;50(5):464-6.

Goyagi T, Tanaka M, Nishikawa T. Fentanyl decreases propofol requirement for laryngeal mask airway insertion. Acta Anaesthesiologica Scandinavica. 2003;47(6):771-4.

Scanlon P, Carey M, Power M. Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone. Canadian J Anaesthesia. 1993;40:816-8.

Brown GW, Patel N, Ellis FR. Comparison of propofol and thiopentone for laryngeal mask insertion. Anarsthesia. 1991;46:771-2.

Denlinger JK, Ellison N, Ominsky AJ. Effects of intratracheal lidocaine on circulatory responses to tracheal intubation. Anesthesiology. 1974;41:409-12.

Abou‐Madi MN, Keszler H, Yacoub JM. Cardiovascular reactions to laryngoscopy and tracheal intubation following small and large doses of lidocaine. Canadian Anaesthet Soc J. 1977;24:12-9.

Stoneham MD, Bree SE, Sneyd JR. Facilitation of laryngeal mask insertion. Effects of lignocaine given intravenously before induction with propofol. Anaesthesia. 1995;50:464-6.

Kirkpatrick MB. Lidocaine topical anesthesia for flexible bronchoscopy. Chest. 1989;96:965-6.

Seavell CR, Cook TM, Cox CM. Topical lignocaine and thiopentone for the insertion of a laryngeal mask airway. Anaesthesia. 1996;51:699-701.

Wilson IG. The laryngeal mask airway in paediatric practice. Br J Anaesthesia. 1993;70(2):124-5.

Wood ML, Forrest ET. The haemodynamic response to the insertion of the laryngeal mask airway: a comparison with laryngoscopy and tracheal intubation. Acta Anaesthesiol Scandinavica. 1994;38:510-3.