A rare mediastinal tumor-fat-forming solitary fibrous tumor
DOI:
https://doi.org/10.18203/2349-3933.ijam20183149Keywords:
Immunohistochemistry, Mediastinum, Solitary fibrous tumorAbstract
Solitary fibrous tumor is uncommon spindle cell mediastinal tumor arising mainly from pleural surface. Authors discuss a clinic-radiological features of Fat forming SFT which is rare variant of SFT in 70yrs old male patients. Initially we kept differential of Liposarcoma, Lymphoma on clinico-radiologically features but later after histopathology and Immunohistochemistery turns out to be Solitary fibrous tumor. Here accurate classification is important as SFT classified as intermediate type (rarely malignant), require wide surgical excision with close follow-up.
References
Gengler C, Guillou L. Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 2006;48(1):63-74.
Liu X, Zhang HY, Bu H, Meng GZ, Zhang Z, Ke Q. Fat-forming variant of solitary fibrous tumor of the mediastinum. Chinese Medical J. 2007;120(11):1029-32.
Gold JS, Antonescu CR, Hajdu C, Ferrone CR, Hussain M, Lewis JJ, et al. Clinicopathologic correlates of solitary fibrous tumors. Cancer. 2002;94(4):1057-68.
Yamazaki K, Eyden BP. Pulmonary lipomatous hemangiopericytoma: report of a rare tumor and comparison with solitary fibrous tumor. Ultrastructural Pathol. 2007;31(1):51-61.
Nielsen GP, Dickersin GR, Provenzal JM, Rosenberg AE. Lipomatous hemangiopericytoma. A histologic, ultrastructural and immunohistochemical study of a unique variant of hemangiopericytoma. Am J Surg Pathol. 1995;19(7):748-56.
Wignall OJ, Moskovic EC, Thway K, Thomas JM. Solitary fibrous tumors of the soft tissues: review of the imaging and clinical features with histopathologic correlation. AJR Am J Roentgenol. 2010;195:W55-62.
Guillou L, Gebhard S, Coindre JM. Lipomatous hemangiopericytoma: a fat-containing variant of solitary fibrous tumor? Clinicopathologic, immunohistochemical, and ultrastructural analysis of a series in favor of a unifying concept. Human Pathol. 2000;31(9):1108-15.
England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol. 1989;13(8):640-58.
Witkin GB, Rosai J. Solitary fibrous tumor of the mediastinum. A report of 14 cases. Am J Surg Pathol. 1989;13(7):547-57.
Fletcher CD. The evolving classification of soft tissue tumours: an update based on the new WHO classification. Histopathology. 2006;48(1):3-12.
