HbA1c as screening biomarker of dyslipidemia in type 2 diabetes mellitus patients

Authors

  • S. P. Tejaswi Pullakanam Department of Biochemistry, Gayatri Vidya Parishad Institute of Health care and Medical Technology, Visakhapatnam, Andhra Pradesh, India
  • Krishna Barla Department of Biochemistry, Gayatri Vidya Parishad Institute of Health care and Medical Technology, Visakhapatnam, Andhra Pradesh, India
  • Ramakrishna Nekkala Department of Biochemistry, Gayatri Vidya Parishad Institute of Health care and Medical Technology, Visakhapatnam, Andhra Pradesh, India
  • Pullaiah Pasupeleti Department of Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20183130

Keywords:

Dyslipidemia, HbA1c, Type 2 diabetes mellitus

Abstract

Background: Patients with diabetes are considered to be at high risk for dyslipidemia and hypertension and therefore vulnerable to cardiovascular diseases. This study describes the possible role of Glycated Hemoglobin (HbA1c) and serum lipid profile as a biomarker for detecting cardiovascular diseases. The aim of present work is to study the role of HbA1c as a screening biomarker for dyslipidemia in patients with type 2 Diabetes Mellitus (T2DM).

Methods: Present study consists of 100 Type 2 DM patients between age 30-75 years along with age and sex matched 100 healthy controls. Fasting Blood samples were collected from all participants for measuring lipid profile, blood sugar (FBS) and HbA1c.

Results: Present study revealed a significantly increased level of glycated hemoglobin (HbA1c) in cases compared to control. HbA1c showed direct and significant correlations with cholesterol, triglycerides and LDL and inverse correlation with HDL in cases when compared to controls.

Conclusions: HbA1c can be used as a potential biomarker for the prediction of Dyslipidemia and CVD.

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Published

2018-07-23

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Original Research Articles