Spirometric evaluation in patients with allergic rhinitis- emphasising need of early diagnosis: a tertiary care experience from Central India


  • Nilesh S. Sonawane Department of Respiratory Medicine, Shri Bhausaheb Hire Govt. Medical College, Dhule, Maharashtra, India
  • Sanjay M. Gour Department of Respiratory Medicine, Indira Gandhi Govt. Medical College, Nagpur, Maharashtra, India
  • Radha P. Munje Department of Respiratory Medicine, Indira Gandhi Govt. Medical College, Nagpur, Maharashtra, India
  • Vandana P. B. Department of Respiratory Medicine, Topiwala National Medical College, Mumbai, Maharashtra, India




Allergic rhinitis, FEV1, Spirometry


Background: Allergic rhinitis is predecessor of Bronchial asthma in most of the cases. Present study was aimed to understand the prevalence of the impaired spirometric changes in patients with allergic rhinitis and to find association with various demographic factors, sputum eosinophilia and eosinophil count in the blood with the impaired Spirometry of these patients.

Methods: Authors conducted a cross sectional study among the patients of allergic rhinitis presented to us in our outpatient department from January 2016 to July 2017. The patient’s with allergic rhinitis either newly diagnosed or already on treatment were included in the study. Standard guidelines as given by ARIA were followed in defining a case of allergic rhinitis. The detailed clinical history was taken, and examination was performed of all the patients and documented. Spirometric evaluation was done using the standard guidelines by a desktop based Spirometry.

Results: The mean age of the study subjects was 30.22±13.13 years with male: female ratio of 0.96. The mean duration of the allergic rhinitis in our study was 3.86±3.34years. The most common complaint was itching sensation of nose followed by paroxysmal sneezing and watering of eyes. About 22.15% of the study subjects have impaired Spirometry. Upon bronchodilator therapy 30% of the study subjects had significant reversibility in FEV1.

Conclusions: About ¼ of present study subjects had impaired Spirometry and about 30% of them had reversibility after bronchodilator therapy. Authors also found that the higher age study subjects had significantly higher impaired Spirometry; persistent allergic rhinitis patients had higher impairment of Spirometry and the patients with higher the sputum eosinophilia had higher impairment in Spirometry.


Chronic Obstructive Pulmonary Disease. Available at: http://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd).

Schofield G, Farooque S. Recommended management and recent advances in allergic rhinitis. Prescriber. 2014 May 5;25(9):21-8.

Kim H, Bouchard J, Renzix PM. The link between allergic rhinitis and asthma: A role for antileukotrienes?. Canadian Resp J. 2008;15(2):91-8.

Varshney J, Varshney H. Allergic rhinitis: An overview. Indian J Otolaryngol Head Neck Surg. 2015 Jun 1;67(2):143-9.

Johns DP, Walters JA, Walters EH. Diagnosis and early detection of COPD using spirometry. J Thoracic Dis. 2014 Nov;6(11):1557.

McNulty W, Usmani OS. Techniques of assessing small airways dysfunction. Eur Clin Respiratory J. 2014 Jan 1;1(1):25898.

Kourosh M, Mohammad G, Masoud M. A single center study of clinical and paraclinical aspects in Iranian patients with allergic rhinitis. Iranian J Allergy Asthma Immunol. 2008;7(3):163-7.

Rao B, Arun BJ, Bhaskar V, Nagaraj N. Study of reversible airway disease in patients with allergic rhinitis. Int J Advances Med. 2016 Dec 29;3(3):687-90.

Agarwal VK, Goyal M, Bist SS. Study of predisposing factor, clinical profile, and complications of allergic rhinitis. Clin Rhinol. 2016;9(2):74-6.

Dahilo E, Quadri O, Uzochukwu T. Prevalence and clinical profile of allergic rhinitis as seen at university of Abuja teaching hospital. IOSR J Dent Med Sci. 2017;16(9):6-11.

Leskelä R, Ruokonen M, Korppi M, Kainulainen H, Paassilta M. Association between allergic rhinitis and lung function in school children with asthma. 2013;17(1):21-6.

Ciprandi G, Pistorio A, Tosca M, Ferraro MR, Cirillo I. Body mass index, respiratory function and bronchial hyperreactivity in allergic rhinitis and asthma. Respir Med. 2009;103(2):289-95.

Ciprandi G, Signori A, Tosca Ma, Cirillo I. Bronchodilation test in patients with allergic rhinitis. Allergy. 2011;66(5):694-8.

Ciprandi G, Cirillo I, Signori A. Impact of allergic rhinitis on bronchi: an 8-year follow-up study. Am J Rhinol Allergy. 2011;25(2):72-6.

Jafari M. Effects of persistent allergic rhinitis on spirometric parameters. J Allergy Ther. 2016;07(05).

Kessel A, Halloun H, Bamberger E, Kugelman A, Toubi E. Abnormal spirometry in children with persistent allergic rhinitis due to mite sensitization: the benefit of nasal corticosteroids. Pediatr Allergy Immunol. 2008 Feb;19(1):61-6.

Bavbek S, Saryal S, Karabiyikoglu G, Misirligil Z. Pulmonary function parameters in patients with allergic rhinitis. J Investig Allergol Clin Immunol. 2003;13(4):252-8.

Tantilipikorn P, Juntabenjapat J, Thongngarm T, Assanasen P, Bunnag C, Thinkhamrop B. Prevalence of impaired lower airway function in Thai patients with allergic rhinitis. Asian Biomed. 2016 Feb 1;10(1):67-74.

Anand KS, Ravi GN, Narasimhaswamy KN. Study of pulmonary function test in allergic rhinitis patients of Sullia, Dakshina Kannada. J Evolution Med Dental Sci. 2016 Oct 3;5(79):5867-70.

Cirillo I, Pistorio A, Tosca M, Ciprandi G. Impact of allergic rhinitis on asthma: effects on bronchial hyperreactivity. Allergy. 2009 Mar;64(3):439-44.

Marra SM, Borges RO, Alves R, Silva DA, Taketomi EA, Segundo GR. Spirometric parameters and levels of interferon gamma and IL-5 in induced sputum from patients with allergic rhinitis or asthma. Am J Rhinol Allergy. 2011 Sep;25(5):e196-9.

Medina L. Characterization the Lung Function of Patients with Allergic Rhinitis Without Asthma. J Allergy Clin Immunol. Elsevier Ltd; 2018;141(2):AB103.

Biloo SR, Dar FA, Ahmad R. Comorbid asthma in allergic rhinitis patients in Kashmir. Clin Rhinol An Int J. 2015;8(3):107-9.

Ajiya A, Kolo E, Nwaorgu OG. Baseline lung function of patients with allergic rhinosinusitis in Kano. Nigerian J Basic Clin Sci. 2015 Jul 1;12(2):116-20.

El-Helaly N, Samy SM, Ibrahim TS, Morcos WM, El-Hoshy HM, Mohamed DA. Pulmonary function changes in allergic rhinitis with or without bronchial asthma. J Am Science. 2012;8:110-4.






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