Published: 2019-05-24

Importance of spirometry, pulse oximetry and hematocrit in chronic obstructive pulmonary disease

Vinay Kumar A., Sai Smarat K., Sony Reddy


Background: To study the correlation of clinical features, spirometry, pulse oximetry assessment and haematocrit abnormalities in chronic obstructive pulmonary disease and to assess the severity of chronic obstructive pulmonary disease by spirometry.

Methods: In the present study total 50 cases were selected on the basis of simple random sampling method from the Department of Pulmonary Medicine, Chalmeda Anand Rao Institute of Medical Sciences, Bommakal, Karimnagar, Telangana, India. During study period from June 2017 to December 2018.

Results:  About 50 patients of chronic obstructive pulmonary disease were studied. Majority of the patients were in the age group of 50-70 years. COPD was seen predominantly in male patients and majorities were smoker. In the majority of patients, the duration of illness was 6-10 years, cough with expectoration was present in all patients. As the number of cigarettes/day and duration increases the severity of the disease also increases in the studied population. In the study, about 40 % of cases were in stage III disease. Computerised spirometry was found to be most sensitive investigation in diagnosing and assessing the severity of the disease in all these cases. As the severity and duration of the disease increases, they are more prone to develop hypoxia and polycythaemia as a complication. In present study 8 patients had hypoxia, as assessed by pulse oximeter.

Conclusions: Computerized spirometry is a very useful investigation in the management of chronic obstructive pulmonary disease. Pulse oximetry is a useful tool in diagnosing periods of oxygen desaturation. Pulse oximetry also useful in monitoring the oxygen therapy during management. Haematocrit analysis is a useful adjunct in assessing the severity of the disease. Polycythaemia, even though uncommon in chronic obstructive pulmonary disease patients is one of the rare but preventable complication with early cessation of smoking and with oxygen therapy.


Chronic obstructive pulmonary disease, Electrocardiogram, Forced vital capacity, Forced expiratory volume in first second

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Reilly JJ Jr, Silverman EK, Shapiro SD. In: Chronic obstructive pulmonary disease. Chapter 314 in Harrison's principles of internal medicine. Braunwald E, Fauci AS, Kasper DL. 18th Ed. Mc-Graw Hill; 2015:2.

Hurd S. The impact of COPD on lung health worldwide: epidemiology and incidence. Chest. 2000;117(2):1S-4.

Trask CH, Cree EM. Oximeter studies on patients with chronic obstructive emphysema, awake and during sleep. New Eng J Med. 1962;266(13):639-42.

York EL, Jones RL, Menon D, Sproule BJ. Effects of secondary polycythemia on cerebral blood flow in chronic obstructive pulmonary disease. Am Rev Resp Dis. 1980;121(5):813-8.

Snider GL, Kleinerman J, Thurlbeck WM, Bengali ZH, Snider GL, Kleinerman J, et al. The definition of emphysema. Report of a national heart, lung and blood institute, division of lung diseases, workshop. Am Rev Resp Dis. 1985;132:182.

Firkin F, Chesterman C, Penington D, Rush B. De Gruchy’s. 5th Ed. Clinical hematology in Medical Practice; 1991.

Fussell KM, Ayo DS, Branca P, Rogers JT, Rodriguez M, Light RW. Assessing need for long-term oxygen therapy: a comparison of conventional evaluation and measures of ambulatory oximetry monitoring. Resp Care. 2003;48(2):115-9.

The chronic bronchitis and emphysema by Nicholas Anthonison. Cecil Textbook of Medicine. 22nd Ed. Ausillo; 2005.

Matthay RA, Niederman MS, Wiedemann HP. Cardiovascular-pulmonary interaction in chronic obstructive pulmonary disease with special reference to the pathogenesis and management of cor pulmonale. Med Clinic North Am. 1990;74(3):571-618.

Cote C, Zilberberg M, Mody SH, Celli B. The prevalence of polycythemia in a chronic obstructive pulmonary disease (COPD) cohort. Chest. 2005;128(4):264S.

Cote C, Zilberberg MD, Mody SH, Dordelly LJ, Celli B. Haemoglobin level and its clinical impact in a cohort of patients with COPD. Europ Resp J. 2007;29(5):923.