Dermatologic clue to renal cell carcinoma: a case report
Keywords:Chicken wire vasculature, Cutaneous metastasis, Malignant renal cell carcinoma, Lymphohematogenous spread
Visceral malignancies often present as cutaneous lesion and are an important clue towards the diagnosis. Authors report a case of a 64 years old male, who presented to us with right hemiparesis and multiple purple-red skin lesions. Systematic evaluation, thorough history and histological examination of the skin lesion showing the characteristic lesion lead to a final diagnosis of Renal Cell Carcinoma. Although in the history and physical examination there was no sign of Renal Cell Carcinoma, but eventually the case turned out to be an extensively spread cancer. This kind of Cutaneous lesions in a case of RCC is a rare phenomenon and has not been frequently mentioned in the previous literature, thus this case reminds us about the importance of a detailed clinical look out in each and every patient and various clues to make a correct and timely diagnosis of systemic diseases. The list of visceral malignancies causing cutaneous metastasis is quite long and requires a battery of test to diagnose the same.
Novick AC, Campbell SC. Renal tumors. In: Campbell MF, Walsh PC, Retik AB, Vaughan ED, Wein AJ, Kavoussi LR, eds. Campbell's Urology. 8th ed. New York: WB Saunders Co Ltd; 2002:2672-2731.
Williams JC, Heaney JA. Metastatic renal cell carcinoma presenting as a skin nodule: case report and review of the literature. J Urol. 1994;152:2094-5.
Ather MH, Masood N, Siddiqui T. Current management of advanced and metastatic renal cell carcinoma. Urology J. 2010;7(1):1-9.
Weiss L, Harlos JP, Torhorst J, Gunthard B, Hartveit F, Svendsen E, et al. Cochrane HR. Metastatic patterns of renal carcinoma: an analysis of 687 necropsies. J Cancer Res Clin Oncol. 1988;1;114(6):605-12.
Lookingbill DP, Spangler N, Helm KF. Cutaneous metastases in patients with metastatic carcinoma: a retrospective study of 4020 patients. J Am Acad Dermatol. 1993;29(2):228-36.
Koga S, Tsuda S, Nishikido M, Matsuya F, Saito Y, Kanetake H. Renal cell carcinoma metastatic to the skin. Anticancer Res. 2000;20(3):1939-40.
Gottlieb MD, Roland JT. Paradoxical spread of renal cell carcinoma to the head and neck. Laryngoscope. 1998;108(9):1301-5.
Opper B, Elsner P, Ziemer M. Cutaneous metastasis of renal cell carcinoma. Am J Clin Dermatol. 2006;1;7(4):271-2.
Pritchyk KM, Schiff BA, Newkirk KA, Krowiak E, Deeb ZE. Metastatic renal cell carcinoma to the head and neck. Laryngoscope. 2002;112(9):1598-602.
Bhatia S, Ng S, Hodder SC. Metastatic cutaneous head and neck renal cell carcinoma with no known primary: case report. Brit J Oral Maxillofacial Surg. 2010;1;48(3):214-5.
Langille G, Taylor SM, Bullock MJ. Metastatic renal cell carcinoma to the head and neck: summary of 21 cases. J Otolaryngol Head Neck Surg. 2008;1;37(4).