Serum electrolyte changes in senile cataract patients at tertiary care teaching hospital in Marathwada region, Maharashtra, India
DOI:
https://doi.org/10.18203/2349-3933.ijam20161077Keywords:
Cataract, Electrolytes, Tertiary care teaching hospital, Marathwada regionAbstract
Background: Cataract is one of the leading causes of blindness in developing countries. The most common type of cataract is senile cataract. The exact pathogenesis of cataract is not known, but it is believed that age, sex, radiation and serum electrolyte changes are important responsible risk factor. Rise in serum sodium level is responsible for formation of cataract. Potassium and chloride are not responsible factor for formation of cataract as that of serum sodium level. The purpose of this study is to estimate serum sodium and potassium in senile cataract patients, as compared to those without cataract.
Methods: This study consists of 100 senile cataract patients and age matched 100 normal healthy individuals without cataract, serum electrolyte is measured by using an electrolyte analyzer.
Results: In our study there is significant rise in serum sodium and chloride levels in cases compare to control group which is statistically significant. Serum potassium levels are in significant.
Conclusion: We have concluded that serum sodium and chloride are important markers of senile cataract formation. Restrictions of salt in the diet delay the process of cataract formation.
References
Barber GW. Physiological chemistry of the eye. Arch Ophthalmol. 1973;89(3):236-55.
Mirsamadi M, Nourmohammadi I, Imamiam M. Comparative study of serum Na+ and K+ levels in senile cataract patients and normal individuals. Int J Med Sci. 2004;1:165-9.
Rewatkar M, Muddeshwa MG, Lokhande M, Ghosh K. Electrolyte imbalance in cataract patients. Ind Med Gaz. 2012;89-91.
Abou-Gareeb I, Lewallen S, Bassett K, Courtright P. Gender and blindness: a meta-analysis of population-based prevalence surveys. Ophthalmic Epidemiol. 2001;8:39-56.
Clark JI, Clark JM. Lens cytoplasmic phase separation. Int Rev Cytol. 2000;192:171-87.
Boulton M, Albon J. Stem cells in the eye. Int J Biochem Cell Biol. 2004;36(4):643.
Brownlee M. Negative consequences of glycation. Metabolism. 2000;49(2 Suppl 1):9-13.
Brubaker RF, Bourne WM. Ascorbic acid content of human corneal epithelium. Invest Ophthalmol Vis Sci. 2000;41(7):1681-3.
Luntz MH. Clinical types of cataract. Duane’s Clinical Ophthalmology. Philadelphia, Lippincott-Raven publishers; 2000:5-7.
Tavani A, Negri E, La Vecchia C. Food and nutrient intake and risk of cataract. Ann Epidemiol. 1996;6: 41-6.
Mathur G, Pai V. Comparison of serum sodium and potassium levels in patients with senile cataract and age-matched individuals without cataract. Indian J Ophthalmol. 2013;59:141-2.
Delamere NA, Paterson CA Crystalline lens. Duane's Foundations of Clinical Ophthalmology. Philadelphia, Lippincott-Raven Publishers; 2001:5-11.
Sargent CR, Cangiano JL, Cabán GB, Marrero E, Maldonado MM. Cataracts and hypertension in salt-sensitive rats. A possible ion transport defect. Hypertension. 1987;9:304-8.
Phillips CI. Cataract: a search for associated or causative factors. Excerpta Med. 1980;34:19-25.
Skarnulis L. Cataract and salt: is there a connection? Medical encyclopedia article. Nucleus Medical Media. 14th March 2016.