Screening of type 2 diabetes mellitus patients for their macrovascular complications in tertiary care hospital

Ragul B., Kiran P. K., A. K. Gupta


Background: Type2 diabetes is characterized by a long asymptomatic period commonly to be diagnosed when complications appear. The risk factors associated with diabetes are age, hypertension, dyslipidemia, smoking, alcohol, obesity & others. The role of early detection and adequate treatment of diabetes and related complications patients and health services is the basis for present study.

Methods: The present study was conducted at S.N. Medical College, Agra, India on 86 consecutive newly diagnosed cases of type 2 diabetes. All individuals aged ≥ 20 years of age, who were not known diabetic, presenting to medicine department were included in the study for the targeted and opportunistic screening duration of January 2011 to June 2012.

Results: The prevalence rates of vascular complications in this study group were analyzed statistically. The findings are the mean age was 54.27±9.27 years.  72.09% of newly diagnosed type 2 diabetes patients were aged above 50 years. Maximum number of patients were overweight (37.20%) followed by obese (32.55%). Hypertension was present in 30.23%, prevalence of CAD was 9.30%, and none had evidence of PVD and Cerebrovascular disease.

Conclusions: Macrovascular complications were present in 9.30% of asymptomatic newly diagnosed type 2 diabetes patients. In the study present study found that there was a significant association of these risk factors were identified and treated as early as possible to decrease the progression of vascular complications. 


Cerebrovascular disease, Coronary artery disease, Peripheral arterial disease, Targeted and opportunistic screening, Type 2 diabetes

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American Diabetes Association: Medical Management of Type 2 Diabetes. 6th Ed. Alexandria, VA, American Diabetes Association, 2008.

Premlata G, Rema M, Mohan V. Complications of Diabetes Mellitus At Diagnosis In South Indian Type 2 Diabetic Patients, from M.V. Diabetes Specialities Centre, Chennai. Int J Diab Dev Countries.1998;18:1-4.

Kiran PK, Ragul B, Gupta AK. Targeted and Opportunistic Screening of Type 2 Diabetes Mellitus Cases in Tertiary Care Hospital Saudi. J Med. 2019;4(6):465-73.

American Diabetes Association: Medical Management of Type 1 Diabetes. 5th Ed. Alexandria, VA, American Diabetes Association, 2008.

Haffner SM, Lehto S, Ronnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;339(4):229-34.

Østergaard J, Hansen TK, Thiel S, Flyvbjerg A. Complement activation and diabetic vascular complications. Clinica Chimica Acta. 2005;361:10-9.

Al-Wakeel JS, Hammad D, Al Suwaida A, Mitwalli AH, Memon NA, Sulimani F. Microvascular and macrovascular complications in diabetic nephropathy patients referred to nephrology clinic. Saudi J Kidney Dis Transpl. 2009;20(1):77-85.

Kalofoutis C, Piperi C, Kalofoutis A, Harris F, Phoenix D, Singh J. Type II diabetes mellitus and cardiovascular risk factors: Current therapeutic approaches. Exp Clin Cardiol. 2007;12(1):17-28.

Lukovitsa TG, Mazzoneb T, Gorelicka PB. Diabetes mellitus and Cerebrovascular Disease. Neuroepidemiol. 1999;18:1-14.

Kannel WB, McGee DL. Diabetes and cardiovascular disease. The Framingham studies. JAMA. 1979;241(19):2035-8.

Premalatha G, Mohan V. Is peripheral vascular disease less common in Indians. Int Diab Dev Countries. 1995;15:68-9.

Burt VL, Harris T. The third National Health and Nutrition Examination Survey: contributing data on aging and health. Gerontologist. 1994 Aug;34(4):486-90.

Rema M, Premkumar S, Anitha B, Deepa R, Pradeepa R, Mohan V. Prevalence of diabetic retinopathy in urban India: The Chennai Urban Rural Epidemiology Study (CURES) eye study. Invest Ophthalmol Vis Sci. 2005;46(7):2328-33.

Fowler MJ. Microvascular and macrovascular complications of diabetes. Clin Diabetes. 2008;26(2):77-82.

Ejigu A. Brief communication: patterns of chronic complications of diabetic patients in Menelik II hospital, Ethiopia. Ethiop J Health Dev. 2000;14(1):113-6.

Herman RM, Brower JB, et al. Prevalence of somatic small fiber neuropathy in obesity. Int J Obes (Lond). 2007;31(2):226-35.

Ginsberg HN. 1996 Diabetic dyslipidemia: basic mechanisms underlying the common hypertriglyceridemia and low HDL cholesterol levels. Diabetes. 1996;45(Suppl 3):S27-30.