DOI: http://dx.doi.org/10.18203/2349-3933.ijam20193596

Role of duplex ultrasonography in patients with renal parenchymal disease: renal resistive index vs serum creatinine level

Yassar Shiekh, Aamir Javed Khan, Shafqat Shabir Bhawani

Abstract


Background: In view of the fact that Brightness (B)-mode ultrasound findings in patients with renal parenchymal disease are profoundly non-specific, this study was carried out to determine the efficiency of color Doppler sonography for assessing renal function. In this series, the relationship between the resistive index (RI) of renal interlobar artery and serum creatinine level was analyzed for any relevant association of this color Doppler index with the serum creatinine level.

Methods: In this prospective cross-sectional study, 40 patients with renal parenchymal disease having serum creatinine level >1.4 mg/dL were chosen midst routine revisits. The control group comprised of 40 normal subjects with serum creatinine levels <1.4 mg/dL. After assessing the kidneys of these subjects with gray-scale ultrasound for presence of any stones, hydronephrosis, and/or space occupying lesions instead of, they were subsequently interrogated with color Doppler sonography and RI calculated.

Results: The mean serum creatinine levels±SD in the case and control groups were 6.7±0.7 mg/dL and 1.0±0.4 mg/dL, respectively. The mean±SD resistive index (RI) was 79.0%±1.8% in the diseased group and 60.3%±0.7% in the healthy subjects (p<0.001). The correlation between the RI and the serum creatinine level was statistically significant (p<0.001).

Conclusions: Resistive index (RI) measurement by color doppler ultrasonography is a reasonable prognosticator of functional outcome in patients with renal parenchymal disease. 


Keywords


Doppler ultrasonography, Gray-scale ultrasound, Interlobar artery, Resistive index, Renal parenchymal disease, Serum creatinine

Full Text:

PDF

References


Quaia E, Bertolotto M. Renal parenchymal diseases: is characterization feasible with ultrasound? Eur Radiol. 2002;12(8):2006-20.

Khati NJ, Hill MC, Kimmel PL. The role of ultrasound in renal insufficiency: the essentials. Ultrasound. 2005;21(4):227-44.

Nori G, Granata A, Leonardi G, Sicurezza E, Septa C. The US color Doppler in acute renal failure. Minerva Urol Nefrol. 2004;56(4):343-52.

Kim SH, Kim WH, Choi BI, Kim CW. Duplex Doppler US in patients with medical renal disease: resistive index VS serum creatinine level. Clin Radiol.1992;46(3):219-20.

Goldberg SB. Diagnostic ultrasound. Lippincott RaVen. 1997:787-863.

Kondo A, Akakura K. Assessment of renal function with color Doppler ultrasound in autosomal dominant polycystic kidney disease. International j urol. 2001;8(3):95-8.

Brkljacic B, Sabljar-Matovinovic M, Putarek K, Soldo D, Morovic-Vergles J, Hauser M. Renal vascular resistance in autosomal dominant polycystic kidney disease: evaluation with color Doppler ultrasound. Acta Radiol. 1997;38(5):840-6.

Sutton D. Textbook of Radiology and Imaging. 7th ed. London: Churchill Livingstone; 2003: 885-1069.

Bertolotto M, Quaia E, Rimondini A, Lubin E, Pozzi Mucelli R. Current role of color Doppler ultrasound in acute renal failure. Radiol Med (Torino). 2001;102(5-6):340-7.

Krumme B. Renal Doppler sonography-update in clinical nephrology. Nephron Clin Pract. 2006;103(2):24-8.

Izumi M, Sugiura T, Nakamura H, Nagatoya K, Imai E, Hori M. Differential diagnosis of prerenal azotemia from acute tubular necrosis and prediction of recovery by Doppler ultrasound Am J Kidney Dis 2000;35(4):713-9.

Pollack HM, McClennan BL. Clinical Urography 2nd ed. Philadelphia: W.B. Saunders; 2000:2546-7.

Nosadini R, Velussi M, Brocco E, Abaterusso C, Carraro A, Piarulli F. Increased Renal Arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria. Diabetes 2006;55(1):234-9.

Keven K, Ates K, Yagmurlu B, Nergizoglu G, Kutlay S, Aras S, et al. Renal Doppler ultrasonographic findings in earthquake victims with crush injury. J Ultrasound Med. 2001;20(6):675-9.

Yoon DY, Kim SH, Kim HD, Na DG, Goo JM, Choi HJ et al. Doppler sonography in experimentally induced acute renal failure in rabbits: resistive index versus serum creatinine levels. Invest Radiol. 1995;30(3):168-72.