A comparative study of intrathecal bupivacaine and levobupivacaine for patients undergoing caesarean section

Authors

  • Kiranpreet Kaur Department of Anaesthesia, Pt. BD Sharma PGIMS Rohtak, Haryana, India
  • Sanjay Johar Department of Anaesthesia, Pt. BD Sharma PGIMS Rohtak, Haryana, India
  • Anil Kumar Department of Anaesthesia, Pt. BD Sharma PGIMS Rohtak, Haryana, India
  • Mamta Jain Department of Anaesthesia, Pt. BD Sharma PGIMS Rohtak, Haryana, India
  • Prashant Kumar Department of Anaesthesia, Pt. BD Sharma PGIMS Rohtak, Haryana, India
  • Anish Singh Department of Anaesthesia, Pt. BD Sharma PGIMS Rohtak, Haryana, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20195229

Keywords:

Bupivacaine, Caesarean section, Levobupivacaine, Local anaesthetics, Spinal anaesthesia

Abstract

Background: The present study was conducted to compare the effects of 0.5% isobaric levobupivacaine and 0.5% hyperbaric bupivacaine in pregnant females undergoing caesarean section.

Methods: Study was conducted on 100 pregnant females undergoing caesarean section. They were randomly divided into two groups B and L receiving 2 ml of 0.5% hyperbaric bupivacaine and 0.5% levobupivacaine respectively. Two groups were compared with regard to sensory block, motor block, haemodynamic stability and complications if any.

Results: Time to achieve sensory blockade till T6 dermatome was prolonged in group B (162.52±80.55 sec) as compared to group L (139.40±49.79 seconds) (p value= 0.087). Prolonged duration of motor blockade was observed in group B (160.76±6.56 minutes) as compared to group L (131.48±14.42 minutes) (p<0.001). Less haemodynamic stability was seen in patients of group B with more incidence of hypotension and bradycardia.as compared to group L.

Conclusions: Levobupivacaine is nearly equally effective to bupivacaine to produce sensory and motor blockade with comparable onset time and better haemodynamic stability with lesser side effects.

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Published

2019-11-25

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Original Research Articles