A study of cardiovascular abnormalities among cirrhosis of liver cases
Keywords:Alcohol, Cardiovascular, Cirrhosis of liver
Background: The correlations between alcohol consumption and cirrhosis of liver have been dealt with great detail. As with the many studies that have looked upon the mortality of the patients with cirrhosis, the speed of progression of the disease and the various situations in which the condition of the patient deteriorates, many have been inconclusive about the reason for death in patients of cirrhosis of liver as the disease progresses.
Methods: This study was conducted in the department of medicine, Vijayanagara Institute of Medical Sciences, a tertiary care hospital in Bellary, Karnataka Study subjects: were a group of 50 patients with alcoholic cirrhosis, a group of 50 patients with non-alcoholic cirrhosis and 50 normal subjects without cirrhosis.
Results: The ECG findings among alcoholics, low voltage complex 10%, long QT3% LAE 8% LVH16%. ST T changes 10%. Among non-alcoholic patients low voltage complex 4% Long QT 2% LAE 7%, LVH 16% ST T changes 16%.
Conclusions: The cardiovascular abnormalities did not show much difference between the alcoholic and non-alcoholic patients.
Chung RT, Podolsky D. Cirrhosis and its complications; in Harrisons Principles of Internal Medicine; 16th ed.; 2005:1858-69.
Sherlock S, Dooley J. Hepatic cirrhosis; in diseases of liver and biliary system; Blackwell Science publishers; 11th ed.; 2011:368-380.
Moore KP, Wong F, Gines, P, Bernardi M, Ochs A, Salerno F, Angeli P, et al. The management of ascites in cirrhosis: report on the consensus conference of the. International Ascites Club. Hepatology. 2003;1(38):258-66.
Kowalski HJ, Abelmann WH. The cardiac output at rest in Laennecs cirrhosis. J Clin Invest. 1953;32:1025-33.
Li CP, Lee FY, Hwang SJ, Chang FY, Lin HC, Lu RH, et al. Spider angiomas in patients with liver cirrhosis: role of alcoholism and impaired liver function. Scand J Gastroenterol. 1999;34(5):520-3.
Bernardi M, Calandra S, Colantoni A, Trevisani F, Raimondo ML, Sica G, et al. Q±T interval prolongation in cirrhosis: prevalence, relationship with severity and etiology of the disease, and possible pathogenetic factors. Hepatology. 1998;27:28-34.
Puddu PE, Bourassa MG. Prediction of sudden death from QTc interval prolongation in patients with chronic ischaemic heart disease. J Electrocardiol. 1986;19:203-12.
Pozzi M, Ratti L, Guidi C, Milanese M, Mancia G. Potential therapeutic targets in cirrhotic cardiomyopathy Cardiovasc Haematolog. Disord Drug Targets. 2007;7:21-6.
Wong F, Girgrah N, Graba J, Allidina Y, Liu P, Blendis L. The cardiac response to exercise in cirrhosis. Gut. 2001;49:268-2.
Møller S, Dümcke CW, Krag A. The heart and the liver. Expert Rev Gastroenterol Hepatol. 2009;3:51-64.