Priapism: a rare presentation in chronic myeloid leukemia

Authors

  • Avtar Singh Dhanju Department of Medicine, Government Medical College, Amritsar, Punjab, India
  • Princy Tyagi Department of Medicine, Government Medical College, Amritsar, Punjab, India
  • Sumitoj Singh Dhaliwal Department of Surgery, Government Medical College, Amritsar, Punjab, India
  • Surender Paul Department of Pathology, Government Medical College, Amritsar, Punjab, India
  • Rajbinder Singh Department of Medicine, Government Medical College, Amritsar, Punjab, India
  • Jasdeep Singh Department of Medicine, Government Medical College, Amritsar, Punjab, India
  • Amardeep Singh Parmar Department of Medicine, Government Medical College, Amritsar, Punjab, India
  • Deepshikha Singla Department of Medicine, Government Medical College, Amritsar, Punjab, India
  • K. Thiyagu Department of Medicine, Government Medical College, Amritsar, Punjab, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20195253

Keywords:

Chronic myeloid leukemia, Complications, Emergency, Priapism

Abstract

Priapism is a rare presenting feature of Chronic Myeloid Leukemia (CML). It is an urological emergency which requires urgent treatment to prevent long term complications, in particular erectile dysfunction. Author report a case of 18 year old male presenting with persistent painful erection of penis for around 14 hours. The patient underwent immediate irrigation and decompression of priapism in emergency and was started on cytoreductive therapy. During hospitalization, peripheral blood smear and bone marrow aspiration confirmed the diagnosis of CML.

References

Broderick GA. Priapism. In: Wein AJ eds. Campbell-Walsh Urology. 11th ed. Philadelphia: Elsevier-Saunders; 2012:669-691.

Tazi I. Priapism as the first manifestation of chronic myeloid leukemia. Annal Saudi Medi. 2009 Sep;29(5):412.

Becerra-Pedraza LC, Jiménez-Martínez LE, Peña-Morfin I, Nava-Esquivel R, Villegas-Martínez JA. Priapism as the initial sign in hematologic disease: Case report and literature review. Int J Surg Case Rep. 2018 Jan 1;43:13-7.

Chang MW, Tang CC, Chang SS. Priapism a rare presentation in chronic myeloid leukemia: case report and review of the literature. Chan Gun Medi J. 2003 Apr 1;26(4):288-92.

Adams BD, Baker R, Lopez JA, Spencer S. Myeloproliferative disorders and the hyperviscosity syndrome. Emerg Medi Clin. 2009 Aug 1;27(3):459-76.

Mulhall JP, Honig SC. Priapism: etiology and management. Acade Emerg Medi. 1996 Aug;3(8):810-6.

Stucki A, Rivier AS, Gikic M, Monai N, Schapira M, Spertini O. Endothelial cell activation by myeloblasts: molecular mechanisms of leukostasis and leukemic cell dissemination. Blood. 2001 Apr 1;97(7):2121-9.

Rodgers R, Latif Z, Copland M. How I manage priapism in chronic myeloid leukaemia patients. Br J Haematol. 2012 Jul;158(2):155-64.

Nerli RB, Magdum PV, Hiremath SC, Patil AY, Pai SV, Handigund RS, et al. Priapism a rare presentation in chronic myeloid leukemia: case report. Urol Case Rep. 2016 Jan 1;4:8-10.

Ergenc H, Varım C, Karacaer C, Çekdemir D. Chronic myeloid leukemia presented with priapism: Effective management with prompt leukapheresis. Nig J Clini Prac. 2015;18(6):828-30.

Downloads

Published

2019-11-25