DOI: http://dx.doi.org/10.18203/2349-3933.ijam20194188

Study comparing the clinical profile of patients with stroke in diabetic and non-diabetic patients

G. Sathish Kumar, S. Rajeswaran, U. B. Padmanaban

Abstract


Background: A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts (or ruptures). Computed tomography (CT) and magnetic resonance imaging (MRI) was done to determine the type of stroke. Diabetes mellitus is a well-recognized risk factor for ischemic stroke. The study was undertaken to assess the clinical characteristics, outcome pattern and to compare the pattern of stroke in diabetics and non-diabetics.

Methods: An observational cross-sectional prospective study wherein a hundred stroke patients being admitted to MGMGH, Trichy were sampled and the clinical profile along with outcome is compared in diabetic and non- diabetic populations and the statistical significance of the same.

Results: The proportion of patients with poor outcome following stroke was significantly higher in diabetics compared with non-diabetic patients being chi square value was 37.6514 and p value was found to be significantly less than 0.0001.

Conclusions: The study resulted the large hemorrhages are twice as much common in the diabetic population compared to the non-diabetic population , the incidence increases with the chronicity of diabetes  and the outcome is superior in the non-diabetics compared to the diabetics admitted in Mahatma Gandhi Memorial Government Hospital, Tiruchirappalli,  Tamil Nadu, India.


Keywords


Diabetes, Hemorrhage, Infarct, Stroke

Full Text:

PDF

References


Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27(5):1047-53.

Chen R, Ovbiagele B, Feng W. Diabetes and stroke: epidemiology, pathophysiology, pharmaceuticals and outcomes. Am J Med Sci. 2016;351(4):380-6.

Kissela BM, Khoury J, Klendorfer D, Woo D, Schneider A, Alwell K, et al. Epidemiology of ischemic stroke in patients with diabetes. The Greater Cincinnati/ Northern Kentucky Stroke Study. Diabetes Care. 2005;28(2):355-9.

Ali R, Kazmi S, Iqbal MZ. Pattern of stroke in diabetics and non-diabetics. J Ayub Med Coll Abbottabad. 2013;25(1-2):89-92.

Sarkar RN, Banerjee S, Basu A. Comparative evaluation of diabetic and non-diabetic stroke-effect of glycaemia on outcome. 2004;102(10):551-3.

Saebo. The Brunnstrom stages of stroke recovery. Available at: https://www.saebo.com/the-stages-of-stroke-recovery/.

Zafar A, Shahid SK, Siddiqui M, Khan FS. Pattern of stroke in type 2 diabetic subjects versus non-diabetic subjects. J Ayub Med Coll Abbottabad. 2007;19(4):64-7.

Mulneir HE, Seaman HE, Raleigh VS, Muthu SSS, Colhoun HN, Lawrenson RA, et al. Risk of stroke in people with type 2 diabetes in UK: a study using the General Practice Research Database. Diabetologia. 2006;49:2859-65.

Ho JE, Paultre F, Mosca L. Is Diabetes Mellitus a Cardiovascular Disease Risk Equivalent for Fatal Stroke in Women?. Diabetes and Stroke Mortality Risk in Women. 2003:2812-6.

Air EL, Kissela BM. Diabetes, the Metabolic Syndrome and Ischemic Stroke. 2007;30(12):3131-40.

Jorgensen H, Nakayama H, Raaschou HO, Olsen TS. Stroke in patients with diabetes. The Copenhagen Stroke Study. Stroke. 1994;25(10):1977-84.

Megherbi SE, Milan C, Minier D, Couvreur G, Osseby GV, Tilling K, et al. Association between diabetes and stroke subtype on survival and functional outcome 3 months after stroke: data from the European Biomed Stroke Project. Stroke. 2003;34(3):688-94.

Tuttolomondo A, Pinto A, Salemi G, Di Raimondo D, Di Sciacca R, Fernandez P, et al. Diabetic and non-diabetic subjects with ischemic stroke: differences, subtype distribution and outcome. Nutr Metab Cardiovasc Dis. 2008;18(2):152-7.

Karapanayiotides T, Piechowski-Jozwiak B, van Melle G, Bogousslavsky J, Devuyst G. Stroke patterns, etiology, and prognosis in patients with diabetes mellitus. Neurol. 2004;62(9):1558-62.