DOI: http://dx.doi.org/10.18203/2349-3933.ijam20161104

Case series of gestation and lactation associated osteoporosis and a review of the literature

Feyzi Gokosmanoglu, Ceyhun Varım, Hasan Ergenc, Cigdem Tura Bahadir, Elif Kilic Kan, Ramis Colak

Abstract


Generalized osteoporosis associated with gestation and lactation is a rarely-seen case, which is seen during the final period of gestation or right after birth/delivery. The etiology and pathogenesis are not fully known. The fact that the pre-existing osteoporosis may be aggravated by gestation, that it may stem from genetic susceptibility, or that it may even be random are still under discussion. The most commonly-seen symptom is particularly the short stature due to lumbar pain during the lactation period as well as the vertebral compression fractures. In this study, we aimed to draw the attention to this rare case seen in the patients applying to the clinic with the complaint of post-natal lumbar pain, by starting from the two cases whose diagnoses and treatments were performed in our clinic.


Keywords


Gestation, Lactation, Osteoporosis

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References


Bonacker J, Janousek M, Kröber M. Pregnancy-associated osteoporosis with eight fractures in the vertebral column treated with kyphoplasty and bracing: a case report. Arch Orthop Trauma Surg. 2014;134:173-9.

Ofluoğlu Ö, Ofluoğlu D. A case report: pregnancy-induced severe osteoporosis with eight vertebral fractures. Rheumatology International. 2008;29 (2);197-201.

Ward AK, Adams JE, Mughal MZ. Bone status during adolesence, pregnancy and lactation. Curr Opin Obstet Gynecol. 2005;17:435-9.

Ozturk C, Atamaz FC, Akkurt H, Akkoc Y. Pregnancy-associated osteoporosis presenting severe vertebral fractures. J Obstet Gynaecol Res. 2014;40:288-92.

Sarpel T, Kozanoğlu E, Guzel R, Goncu K. Pregnancy associated oseoporosis: seven cases of pregnancy asociated osteoporosis discussed. Osteoporos Int. 2000;2:326-144.

Kamimura M, Uchiyama S, Nakagawa H. The bone metabolic conditions in pregnancy and lactation-associated osteoporosis. Orthopedic Surgery. 2011;VII:189-92.

Nakamura Y, Kamimura M, Ikegami S, Mukaiyama K, Komatsu M, Uchiyama S et al. A case series of pregnancy- and lactation associated osteoporosis and a review of the literature. Ther Clin Risk Manag. 2015;11:1361-5.

Di Gregorio S, Danilowicz K. Osteoporosis with vertebral fractures associated with pregnancy and lactation. Nutrition. 2000;16:1052-5.

Güzel R, Başaran S. Kalçanın Geçici Osteoporozu. Türk Fiz Tıp Rehab Der. 2009:55(1);41-5.

La Montagna G, Malesci D, Tirri R, Valentini G. Successful neridronate therapy in transient osteoporosis of the hip. Clin Rheumatol. 2005;24:67-9.

Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP. Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2011;96(7):1911-30.

Karlsson K, Ahlborg HG, Caroline K. Maternity and bone mineral density. Acta Orthopaedica. 2005;76(1):2-13.

Joanna D, Wanda HS. Pregnancy associated osteoporosis-a case report. Ginekol Pol. 2012;83:377-9.

Winarno AS, Kyvernitakis I, Hadji P. Successful treatment of 1-34 parathyroid hormone (PTH) after failure of bisphosphonate therapy in a complex case of pregnancy associated osteoporosis and multiple fractures. Z Geburtshilfe Neonatol. 2014;218:171-3.

Hadgaonkar S, Shah KC, Bhatt H, Shyam A, Sancheti P. Post pregnancy severe spinal osteoporosis with multiple vertebral fractures and kyphoscoliosis in a multigravida: a rare case with management. Asian Spine J. 2015;9(4):625-8.