Response of bisphosphonate therapy in recurrent tumoral calcinosis

Authors

  • Manish Shrivastav Department of Endocrinology, LLRM Medical College and SVBP Hospital, Meerut, Uttar Pradesh, India
  • Nihit Kharkwal Department of Endocrinology, LLRM Medical College and SVBP Hospital, Meerut, Uttar Pradesh, India
  • Alankar Tiwari Department of Endocrinology, LLRM Medical College and SVBP Hospital, Meerut, Uttar Pradesh, India
  • Keshav Kumar Gupta Department of Endocrinology, LLRM Medical College and SVBP Hospital, Meerut, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20200089

Keywords:

Calcinosis, Di(bis)phosphonate, Hyperphosphatemia, Parathyroid hormone

Abstract

Tumoral calcinosis is a rare condition characterized by solitary or multiple, periarticular masses. Surgical excision of the tumoral calcinosis lesion is a well-documented treatment, but recurrences are not uncommon. A case of 42 year old male patient of tumoral calcinosis presented to us with history of repeated surgical excision twice in past 8 years for recurrent swellings. He was started on IV zoledronic acid and the patient has shown improvement after two years with no recurrence in follow up.

References

Möckel G, Buttgereit F, Labs K, Perka C. Tumoral calcinosis revisited: pathophysiology and treatment. Rheumatol Int. 2005;25(1):55-9.

Shirasuna K, Sugiyama M, Yasui Y. Tumoral calcinosis around the mandibular condyle. Int J Oral Maxillofac Surg. 1991;20:36-7.

Mozaffarian G, Lafferty FW, Pearson OH. Treatment of tumoral calcinosis with phosphorus deprivation. Ann Intern Med. 1972;77:741-5.

Olsen KM, Chew FS. Tumoral calcinosis: pearls, polemics, and alternative possibilities. Radiographics. 2006;26:871-85.

Steinbach LS, Johnston JO, Tepper EF, Honda GD, Martel W. Tumoral calcinosis: radiologic-pathologic correlation. Skeletal Radiol. 1995;24:573-8.

Davies M, Clements MR, Mawer EB, Freemont AJ. Tumoral calcinosis: clinical and metabolic response to phosphorus deprivation. Q J Med. 1987;63:493-503.

Jacob JJ, Mathew K, Thomas N. Idiopathic sporadic tumoral calcinosis of the hip: Successful oral bisphosphonate therapy. Endocrine Pract. 2007;13:182-6.

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Published

2020-01-23

Issue

Section

Case Reports