Hyperuricemia among hypertensive and normotensive individuals: a case control study


  • Pradeep Raj Meenakshi Sundaram Department of General Medicine, Sri Muthukumaran Medical College and Research Institute, Chennai, Tamil Nadu, India
  • Ravin Devasir Sathyaseelan Department of General Medicine, Sri Muthukumaran Medical College and Research Institute, Chennai, Tamil Nadu, India
  • Srisanthanakrishnan V. Department of Community Medicine, Sri Muthukumaran Medical College and Research Institute, Chennai, Tamil Nadu, Indiai




Hyperuricemia, Hypertension, Normotensive individuals, Serum uric acid


Background: The depth of association between hypertension and serum uric acid remains a mystery. In order to know the exact association between hypertension and serum uric acid, authors intended to investigate the serum uric acid levels among hypertensive and non-hypertensive patients and, authors assessed whether hyperuricemia increases with increasing duration of hypertension and severity of hypertension.

Methods: This case control study was conducted among hypertensive (Cases) and non-hypertensive patients (Controls) attending outpatient and inpatient department of general medicine in Sri Muthukumaran Medical College and Research Institute during January 2019 to March 2019. A total of hundred patients were included in this study with fifty cases and control each. Data was conducted using a proforma, covering particulars related to hypertension and the levels of serum uric acid were also noted in the same.  Data analysis was done using SPSS.

Results: Hyperuricemia among cases and control was found to be statistically significant association with odds ratio of 3.7. Also, the study showed that the serum uric acid levels were significantly increased in patients with Stage 2 hypertension compared to stage 1 hypertension. Also, cases with longer duration of hypertension had significantly raised serum uric acid levels compared to cases with lesser duration of hypertension.

Conclusion: Assessment of serum uric acid may be recommended for all the hypertensive cases.


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