Tumoral calcinosis, a diagnostic dilemma: a case report

Authors

  • Javed Altaf Department of Surgery, Hamdard Institute of Medical Sciences and Research, New Delhi, India
  • Tajamul Rashid Department of Surgery, Hamdard Institute of Medical Sciences and Research, New Delhi, India
  • Musharraf Husain Department of Surgery, Hamdard Institute of Medical Sciences and Research, New Delhi, India
  • Mohammad Arif Department of Surgery, Hamdard Institute of Medical Sciences and Research, New Delhi, India
  • Manzoor Ahmad Department of Surgery, Hamdard Institute of Medical Sciences and Research, New Delhi, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20203130

Keywords:

Chronic renal failure, Hyperphosphatemia, Normophosphatemia, Tumoral calcinosis

Abstract

Tumoral calcinosis is a rare diagnosis characterized by deposition of calcium salts in peri-articular soft tissue regions. It is divided into primary and secondary varieties. The primary tumoral calcinosis is further divided into two types; primary hyperphosphatemic type and primary normophosphatemic type. The secondary variety occurs in association with chronic renal failure. Biochemical assessment and typical radiographic features help in diagnosis. Mainstay of treatment for primary variety is surgical. Secondary variety is mainly treated by medical measures. Surgical intervention is reserved for patients who do not respond to medical therapy.

References

Inclan A, Leon PP, Camejo M. Tumoral calcinosis. J Am Med Ass. 1943;121:490-5.

Pakasa NM, Kalengayi RM. Tumoral calcinosis: a clinicopathological study of 111 cases with emphasis on the earliest changes. Histopathol. 1997;31:18-24.

Asuncion GF, Tzarnas CD. Uremic tumoral calcinosis: acute hand presentations mimicking infection. J Hand Surg Am. 1994;19:809-12.

Olsen KM, Chew FS. Tumoral calcinosis: pearls, polemics, and alternative possibilities. Radiographics. 2006;26:871-85.

Fathi I, Sakr M. Review of tumoral calcinosis:A rare clinicopathological entity. World J Clin Cases. 2014;2(9):409-14.

Petscavage JM, Richardson ML. Tumoral calcinosis mimicking recurrent osteosarcoma. J Radiol Case Rep. 2009;4:336.

Hershkovitz D, Gross Y, Nahum S, Yehezkel S, Sarig O, Uitto J, et al. Functional characterization of SAMD9, a protein deficient in normophosphatemic familial tumoral calcinosis. J Invest Dermatol. 2011;131:662-9.

Hug I, Gunçaga J. Tumoral calcinosis with sedimentation sign. Br J Radiol. 1974;47:734-6.

Martinez S, Vogler JB, Harrelson JM, Lyles KW. Imaging of tumoral calcinosis: new observations. Radiology. 1990;174:215-22.

Steinbach LS, Johnston JO, Tepper EF, Honda GD, Martel W. Tumoral calcinosis: radiologic-pathologic correlation. Skeletal Radiol. 1995;24:573-8.

Farzan M, Farhoud AR. Tumoral calcinosis: what is the treatment? Report of two cases of different types and review of the literature. Am J Orthop (Belle Mead NJ). 2011;40:E170-6.

Downloads

Published

2020-07-21

Issue

Section

Case Reports