Role of comprehensive diabetes care in known diabetes patients from Gujarat state
Keywords:Ayurveda, Comprehensive diabetes care, Diabetes mellitus, Panchkarma
Background: Diabetes mellitus (DM) stays as one of the audacious worldwide plagues of the twenty-first century. As per an epidemiological study done in Gujarat, prevalence rate of DM was found to be >8%. CDC therapy is Panchkarma based Ayurvedic therapy for the management of DM. The aim of the present study was to analyze the effectiveness of CDC in patients of DM.
Methods: This was a retrospective study conducted at Madhavbaug clinics located in Gujarat, wherein we identified the data of obese patients suffering from type 2 DM (HbA1c ≥6.5%) of either gender and any age. Out of these, data of patients who had been administered CDC with minimum 6 sittings over a span of 12 weeks were considered for the study.
Results: Out of 98 patients, number of patients with controlled DM status increased and that with uncontrolled status reduced at week 12, and the mean HbA1c reduced from 8.55 at baseline to 7.15 at week 12 of CDC therapy. Other anthropometric, cardiorespiratory parameters showed statistically significant improvement after 12 week of CDC therapy as compared to baseline, and the consumption of allopathic medications was also significantly reduced.
Conclusions: From the findings of the present study, it can be concluded that CDC can serve as effective therapy for management of type 2 DM.
Singh PS, Sharma H, Zafar KS, Singh PK, Yadav SK, Gautam RK, et al. Prevalence of type 2 diabetes mellitus in rural population of India- a study from Western Uttar Pradesh. Int J Res Med Sci. 2017;5:1363-7.
Koria B, Kumar R, Nayak A, Kedia G. Prevalence of diabetes mellitus in urban population of Ahmadabad city, Gujarat. Natl J Community Med. 2013;4(3):398-401.
Forbes JM, Cooper ME. Mechanisms of Diabetic Complications. Physiol Rev. 2013;93:137-88.
Clinical importance of Glycosylated hemoglobin (HbA1c) in diabetes mellitus patients. Available at: https://www.researchgate.net/publication/26575867_Clinical_Importance_Of_Glycosylated_Hemoglobin_HbA1c_In_Diabetes_Mellitus_Patients. Accessed on 11 March 2018.
Buse JB, ACCORD Study Group. Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial: design and methods. Am J Cardiol. 2007;99(12A):21i-33i.
Matthaei S, Bierwirth R, Fritsche A, Gallwitz B, Haering HU, Joost HG, et al. Medical antihyperglycaemic treatment of type 2 diabetes mellitus. Exp Clin Endocrinol Diabe. 2009;117:522-57.
Egede LE, Gebregziabher M, Dismuke CE, Lynch CP, Axon RN, Zhao Y, et al. Medication nonadherence in diabetes. Diabetes Care. 2012;35:2533-9.
Modak M, Dixit P, Londhe J, Ghaskadbi S, Devasagayam TP. Recent advances in Indian herbal drug research guest editor: Thomas Paul Asir Devasagayam Indian herbs and herbal drugs used for the treatment of diabetes. J Clin Biochem Nutr. 2007;40(3):163-73.
Young E, Okafor C, Okwara C. Diabetes mellitus, associated co-morbidities and complications - A review. J Med Med Sci. 2016;7(3):47-55.
Tripathi K, Srivastava A. Diabetes mellitus: Complications and therapeutics. Med Sci Monit. 2006;12(7):130-47.
Singh N. Panchakarma: Cleaning and Rejuvenation Therapy for Curing the Diseases. J Pharmacognosy Phytochem. 2012;1(2):1-9.
Rastogi S, Chiappelli F. Hemodynamic effects of Sarvanga Swedana (Ayurvedic passive heat therapy): A pilot observational study. Ayu. 2013;34(2):154-9.
Nair D. Understanding the Role of Ayurveda Panchakarma Therapy W.S.R. to Vasthi (Enema) in the Management of Type II Diabetes Mellitus- A Case Review. Int J Complement Alt Med. 2017;8(6):00276.
Lawrence S, Sangeetha K. A review on the mode of action of sneha in koshta during sodhana snehapana. Int J Res Ayurveda Pharm. 2018;9(3):21-4.
Gerstein HC, Riddle MC, Kendall DM, Cohen RM, Goland R, Feinglos MN, et al. Glycemia treatment strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Am J Cardiol. 2007;99(12A):34i-43i.
Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med. 2008;358(24):2545-59.
Alawdi S. Effect of Medication Adherence to Oral Hypoglycemic Drugs on Glycemic Control in Type 2 Diabetic Patients: a Cross Sectional Study. Saudi J Med Pharm Sci. 2019;5(6):543-7.