A comparative study to compare the efficacy of hyperbaric bupivacaine alone and hyperbaric bupivacaine with clonidine in caudal block in paediatric lower abdominal surgeries

Authors

  • Roopal Rambhai Garaniya Department of Anaesthesiology, B. J. Medical College, Ahmedabad, Gujarat, India
  • Vaishali Gautam Department of Anaesthesiology, B. J. Medical College, Ahmedabad, Gujarat, India
  • Ritu Ruparel Department of Anaesthesiology, B. J. Medical College, Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20170071

Keywords:

Bupivacaine, Clonidine, Infraumbilical surgeries, Post op analgesia, Sedation score, FLACC score

Abstract

Background: The aim was to compare the efficacy of addition of clonidine to hyperbaric bupivacaine and to compare it with plain hyperbaric bupivacaine for caudal analgesia in children aged 3 months to 3 years in term of analgesic duration, hemodynamic change and degree of sedation.

Methods: Sixty ASA I and II children undergoing lower abdominal surgeries were divided into two groups of 30 each, plain hyperbaric bupivacaine group (Group B) and hyperbaric bupivacaine with clonidine group (Group C). Group B received only bupivacaine and Group C received bupivacaine with clonidine in caudal block.

Results: Hemodynamic and demographic profiles were comparable between both the groups. Addition of clonidine significantly prolonged duration of caudal analgesia and significantly reduce the FLACC scores in group C as compared to group B. Mean sedation score immediately after postoperative period was higher in group C but after 4 hours of awakening, there was gradual fall in mean sedation score in both groups.

Conclusions: Addition of clonidine to bupivacaine in caudal analgesia significantly increases the duration of post-operative analgesia.

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References

Sharpe P, Klein JR, Thompson JP, Rushman SC, SherwinJ et al. Analgesia for circumcision in a paediatric population:comparison of caudal bupivacaine alone with bupivacaine plus two doses of clonidine. Paediatr Anaesth. 2001;11(6):695-703.

Manickam A, Vakamudi M, Parameswari A. Efficacy of clonidine as an adjuvant to ropivacaine for caudal analgesia in children undergoing subumbilical surgery. J Anaestheiol Clinical Pharmacol. 2012;28:185-9.

Klimscha W, Chiari A, Michal A. The efficacy and safety of a clonidine/bupivacaine combination in caudal blockade for paediatric hernia repair. Anaesth Analg. 1998;86(1):54-61.

Neogi M, Bhattacharjee DP, Dawn S, Chatterjee N. A comparative study between clonidine and dexmedetomidine used as adjuncts to ropivacaine for caudal analgesia in paediatric patients. J Anaesthesiol Clin Pharmacol. 2010;26:149-53.

Parameswari A, Dhev AM, Vakamudi M. Efficacy of clonidine as an adjuvant to bupivacaine for caudal analgesia in children undergoing sub-umbilical surgery. Indian J Anaesthesia. 2010;54(5):458-63.

Hennawy A, Elwahab AM, Elmaksoud AM, El-Ozairy HS. Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children. Br J Anaesth. 2009;103:268-74.

Negri P, Ivani G, Visconti CD. How to prolong postoperative analgesia after caudal anaesthesia with ropivacaine in children: S-ketamine versus clonidine. Paediatr Anaesth. 2001;11(6):679-83.

Samir J, Sylvaine M, Christian B, Dubousset AM. Clonidine in paediatric caudal anaesthesia. Anaesth Analg. 1994;78:663-6.

Koul A, Pant D, Sood J. Caudal clonidine in day-care paediatric surgery. Indian J Anaesthesia. 2009;53(4):450-4.

Joshi W, Connelly NR, Freeman K. Analgesic effect of clonidine add to bupivacaine 0.125% in paediatric caudal blockade. Paediatr Anaesth. 2004;14(6):483-6.

Lee J, Rubin AP. Comparison of a bupivacaine –clonidine mixture with plain bupivacaine for caudal analgesia in children. British J Anaesthesia. 1994;72:28-6.

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Published

2017-01-23

How to Cite

Garaniya, R. R., Gautam, V., & Ruparel, R. (2017). A comparative study to compare the efficacy of hyperbaric bupivacaine alone and hyperbaric bupivacaine with clonidine in caudal block in paediatric lower abdominal surgeries. International Journal of Advances in Medicine, 4(1), 51–55. https://doi.org/10.18203/2349-3933.ijam20170071

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Original Research Articles