Assessment of prevalence of anemia and study of anemic patients in population of Nanded district
DOI:
https://doi.org/10.18203/2349-3933.ijam20205044Keywords:
Anemia, Ferritin, Vitamin B12Abstract
Background: Anemia is one of the most common health problems in India. Understanding the variations among the prevalence of anemia between population groups in this large and heterogeneous country is crucial to inform relevant health policy and health service interventions. The present study was conducted to assess prevalence of anemia in the population of Nanded district, Maharashtra.
Methods: All subjects between 13-70 years of age were enrolled in the study for screening of prevalence of anemia. Under complete aseptic conditions, 10 ml of blood was withdrawn from antecubital vein and 2 ml was used for complete blood count estimation and for further blood investigations as necessary. Various hematological parameters were tested in correlation to history and clinical examination of the patients. All data thus obtained was arranged in tabulated form and analyzed using SPSS software.
Results: There were a total of 2190 subjects evaluated, out of these 560 were anemic and 1630 were non-anemic. Out of 560 anemic subjects, 420 were of female gender and remaining 140 were male. The mean iron levels were 64±34 μg/dl. The mean screen ferritin levels were 201±183 ng/dl.
Conclusions: There were 26% of subjects in our study who were anemic, and majority of them were females Although, Iron deficiency anemia revealed as a most common type of anemia, vitamin B12 and folic acid deficiencies also contributed significantly to nutritional anemias. The disease widely occurs and affects mostly children of growing age, females in reproductive ages and elderly population.
References
Kassebaum NJ. The global burden of anemia. Hematol Oncol Clin North Am. 2016;30:247-308.
National consultation on control of nutritional anemia in India. Department of Family Welfare (Maternal Health Division), Ministry of Health and Family Welfare, Nirman Bhawan, New Delhi, 1998.
Seshadri S. A database on iron deficiency anemia (IDA) in India: prevalence, causes, consequences and strategies for prevention. Department of Foods and Nutrition. WHO Collaborating Centre for Nutrition Research. The Maharaja Sayajirao University of Baroda, Vadodara, India, 1999.
Kassebaum NJ, Arora M, Barber RM. Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388:1603-58.
Ferrucci L, Balducci L. Anemia of aging: The role of chronic inflammation and cancer. Semin Hematol. 2008;45:242- 9.
Haider BA, Olofin I, Wang M, Spiegelman D, Ezzati M, Fawzi WW. Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis. BMJ. 2013;346:f3443.
WHO. Nutritional anaemias: tools for effective prevention. Geneva: World Health Organization, 2017.
Kassebaum NJ, Jasrasaria R, Naghavi M. A systematic analysis of global anemia burden from 1990 to 2010. Blood. 2014;123:615-24.
Allen LH, de Benoist B, Dary O, Hurrell R. Guidelines on food fortification with micronutrients. Geneva: World Health Organization, Food and Agricultural Organization of the United Nations, 2006. http://apps.who.int/iris/ bitstream/10665/43412/1/9241594012_eng. pdf?ua=1. Accessed on Sept 27, 2019.
Hall A, Horton S, de Silva N. The costs and cost-effectiveness of mass treatment for intestinal nematode worm infections using different treatment thresholds. PLoS Negl Trop Dis. 2009;3:e402.
World Health Organization/UNICEF/UNU. Iron Deficiency Anaemia: Assessment, Prevention, and Control. A Guide for Programme Managers. Geneva, Switzerland World Health Organization; 2001.
Gupta AK, Damji A, Uppaluri A. Vitamin B12 deficiency. Prevalence among South Asians at a Toronto clinic. Can Fam Physician. 2004;50:743-7.
Nath I, Reddy KS, Dinshaw KA, Bhisey AN, Krishnaswami K, Bhan MK et al. Country profile: India. Lancet. 1998;351:1265-75.
DeMaeyer E, Adiels-Tegman M. The prevalence of anaemia in the world. World Health Stat Q. 1985;38:302-16.
Gupta CP. Role of Iron (Fe) in Body. IOSR J App Chem. 14;11(7):38-46.
Murray CJL, Salomon JA, Mathers CD, Lopez AD. The global burden of disease. Geneva: World Health Organization; 2002.
WHO. Young People’s Health. A Challenge for society. WHO Technical Report Series no 731. Geneva, Switzerland: WHO; 1986.
Aguayo VM, Paintal K, Singh G. The adolescent girls’ anaemia control programme: a decade of programming experience to break the inter-generational cycle of malnutrition in India. Public Health Nutr. 2013;16(9):1667-76.
Balarajan Y, Ramakrishnan U, Ozaltin E, Shankar AH, Subramanian SV. Anaemia in low-income and middle- income countries. Lancet. 2011;378(9809):2123-35.
Guidelines for control of iron deficiency anaemia. National Iron+ Initiative. Towards infinite potential in an anaemia free India. New Delhi: Ministry of Health and Family Welfare, Government of India; 2013.
Carmel R. Efficiency and safety of fortification and supplementation with vitamin B12: Biochemical and physiological effects. Food Nutr Bull. 2008;29 (2):S177-87.
Hoffbrand AV. Megaloblastic anemias. In: Fauci SA, Kasper LD, Longo LD, Hauser LS, Jameson LJ, Loscalzo J (eds). Harrison’s principles of internal medicine. Volume 1. 18th ed. Pennsylvania: McGraw-Hill; 2012:862-72.
Hoffbrand V, Moss PAH, Pettit JE. Megaloblastic anaemias. In: Essential haematology. 5th ed. Massachussetts: Wiley-Blackwell. 2006:44-57.
Desai HG, Antia FP. Vitamin B12 malabsorption due to intrinsic factor deficiency in Indian subjects. Blood. 1972;40:747-53.
Patel KV. Epidemiology of anemia in older adults. Semin Hematol. 2008;45:210-7.
