A study on clinical profile of acute stroke

Authors

  • Avinash Itagi Department of General Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka
  • Bharat G. Department of General Medicine, Koppal Institute of Medical Sciences, Koppal, Karnataka
  • Pooja Biradarpatil Department of General Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka
  • Laxmi Pattanashetti Department of Pharmacology, KLE College of Pharmacy, Hubballi, Karnataka

DOI:

https://doi.org/10.18203/2349-3933.ijam20204966

Keywords:

Ischemic stroke, Hypertension, Clinical profile

Abstract

Background: Stroke or cerebrovascular accident is one of the leading causes of morbidity and mortality in adult life. Ischemic strokes are most common type of strokes and they account for 80-85% of cerebrovascular accidents worldwide. Hypertension, diabetes, dyslipidemia and smoking have been identified as major risk factors. Present study was undertaken to evaluate the clinical and investigation profile of different types of strokes.

Methods: A total of 100 patients with brain stroke from November 2015 to October 2016 were included.  Adult patients with stroke who attended the emergency department within 24 hours of attack were included. Patients with known chronic liver or kidney diseases, transient ischemic attack, active infections, history of neoplasia and alcoholic patients were excluded from the study. A thorough physical examination was conducted and stroke was defined as per World Health Organization criteria. Blood investigations were done including Magnetic resonance imaging and computed tomography scan. The data obtained was coded and entered into Microsoft excel worksheet. The data was analyzed using SPSS statistics software version 20.0.  

Results: Majority of the patients (71.00%) were males and 29.0% of the patients were females. Most of the patients were aged between 61 to 70 years (27.00%). Most of the patients had ischaemic stroke (80.00%) followed by haemorrhagic stroke (20%).

Conclusions: Ischemic stroke is the more common as compared to hemorrhagic stroke. Detection of vascular risk factors and primary prevention measures should be initiated during late adolescence or early adulthood.

Author Biographies

Avinash Itagi, Department of General Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka

Department of Medicine, Assistant Professor.

Bharat G., Department of General Medicine, Koppal Institute of Medical Sciences, Koppal, Karnataka

Department of General Medicine, Assistant Professor

Pooja Biradarpatil, Department of General Medicine, Karnataka Institute of Medical Sciences, Hubballi, Karnataka

Department of General Medicine

Laxmi Pattanashetti, Department of Pharmacology, KLE College of Pharmacy, Hubballi, Karnataka

Department of Pharmacology,Assistant Professor

References

Goldstein M, Barnett HJM, Orgogozo JM, Sartorius N. Recommendations on stroke prevention, diagnosis, and therapy. Report of the WHO Task Force on Stroke and other Cerebrovascular Disorders. Stroke. 1989;20:1407-31.

Shah B, Mathur P. Workshop Report on Stroke Surveillance in India, Division of noncommunicable Diseases. New Delhi, India: Indian Council Med Res. 2006.

Govt. of India, Central Bureau of Health Intelligence, National Health Profile 2008. New Delhi: Directorate General Health Sci. 2008;102.

Prasad K, Singhal KK. Stroke in young: An Indian perspective. Neurol India. 2010;58:343-50

Hariklia VD, Apostolos H, Haralambosk. The Role of Uric Acid in Stroke. The issue Remains Unresolved. Neurologist. 2008;14:238-42.

Anand K, Chowdhury D, Singh KB, Pandav CS, Kapoor SK. Estimation of mortality and morbidity due to strokes in India. Neuroepidemiol. 2001;20(3):208-11.

Schellinger PD, Fiebach JB, Mohr A, Ringleb PA, Jansen O, Hacke W. Thrombolytic therapy for ischemic stroke--a review. Part II--Intra-arterial thrombolysis, vertebrobasilar stroke, phase IV trials, and stroke imaging. Crit Care Med. 2001;29(9):1819-25.

Sethi PK. Stroke-Incidence in India and Management of Ischaemic stroke. Neurosci. 2002;6(3):139-43.

Nagaraja D, Gururaj G, Girish N, Panda S, Roy AK, Sarma GRK et al. Feasibility study of stroke surveillance: data from Bangalore, India. Indian J Med Res. 2009;130:396-403.

Ferri CP, Acosta D, Guerra M, Huang Y, Llibre-Rodriguez JJ, Salas A et al. Socioeconomic factors and all cause and cause-specific mortality among older people in Latin America, India, and china: a population-based cohort study. PLoS Med. 2012;9(2):e1001179.

Kameshwar P, Singhal Kapil K. Stroke in young: an Indian perspective. Neurol India. 2010;58(3):343-50.

Dalal PM, Malik S, Bhattacharjee M, Trivedi ND, Vairale J, Bhat P et al. Population-bases stroke survey in Mumbai, India: incidence and 28-day case fatality. Neuroepidemiol. 2008;31:254-61.

Sethi P. Stroke-incidence in India and management of ischemic stroke. Neurosci. 2002;4(3):139-41.

Das S, Banerjee T. Stroke Indian scenario. Circulation. 2008;118:2719-24.

Eapen RP, Parikh JH, Patel NT. A study of clinical profile and risk factors of cerebrovascular stroke. Gujarat Med J. 2009;64(2):47-54.

Powell JL, Cook IG. Global ageing in comparative perspective: a critical discussion. Int J Sociol Soc Policy. 2009;29:388-400.

Warlow CP, Van Gijn J, Dennis MS, Wardlaw JM, Bamford JM, Hankey GJ et al. Introduction. In: Stroke: Practical Management. 3rd ed. Oxford: Wiley-Blackwell. 2008:1-5.

Mensah GA. Epidemiology of stroke and high blood pressure in Africa. Heart. 2008;94:697-705.

World Health Organization. The world health report 2002; reducing risks, promoting life. Geneva: WHO; 2004. Available at: http://whqlibdoc.who.int/ whr/2002/WHR_2002_(chp4).pdf. Accessed on 3 September 2020.

Sridharan SE, Unnikrishnan JP, Sukumaran S, Sylaja PN, Nayak SD, Sarma PS et al. Incidence, types, risk factors, and outcome of stroke in a developing country: The Trivandrum Stroke Registry. Stroke. 2009;40:1212-8.

Mehndiratta MM, Agarwal P, Sen K, Sharma B. Stroke in young adults. Study from a university hospital in North India. Med Sci Monit. 2004;10(9):CR535-41.

Zunni FS, Ahmed M, Hassan KM, Prakash PS. Stroke: Incidence and pattern in Benghazi Libya. Ann. Saudi Med. 1995;15:32-7.

Tan KS, Navarro JC, Wong KS, Huang YN, Chiu HC, Poungvarin N et al. Clinical profile, risk factors and aetiology of young ischaemic stroke patients in Asia: A prospective, multicentre, observational, hospital-based study in eight cities. Neurol Asia. 2014;1;19(2):117-27.

Banerjee TK, Choudhury D, Das A, Sekhar A, Roy D, Sen S. Analysis of hospital-based stroke registry in a neurological centre in Kolkata. J Indian Med Assoc. 2005;103(12):665-8.

Kannel WB, McGee DL. Diabetes and cardiovascular disease: the Framingham Study. JAMA. 1979;241:2035-8.

Chapman JM, Reeder LG, Borun ER, Clark VA, Coulson AH. Epidemiology of vascular lesions affecting the central nervous system: the occurrence of strokes in a sample population under observation for cardiovascular disease. Am J Public Health. 1966;56:91.

Garvey WT, Hermayer KL. Clinical implications of the insulin resistance syndrome. Clin Cornerstone. 1998;1:13-28.

Wasay M, Khatri IA, Kaul S. Stroke in South Asian countries. Nature Rev Neurol. 2014;10:135-43.

Das SK, Banerjee TK, Biswas A, Roy T, Raut DK, Mukherjee CS, et al. A prospective community-based study of stroke in Kolkata, India. Stroke. 2007;38:906-10.

Nagaraja D, Gururaj G, Girish N, Panda S, Roy AK, Sarma GR, et al. Feasibility study of stroke surveillance: data from Bangalore, India. Indian J Med Res. 2009;130:396-403.

Feigin V, Lawes C, Bennet D, Barker-Cello S, Parag V. Worldwide stroke incidence and early case fatality in 56 population based studies:a systematic review. Lancet Neurol. 2009;8(4):355-69.

Chandana VV, Kalyani N. Clinical Profile of Stroke among Young Adults. Int J Contemp Med Res. 2017;4(11):2280-83.

Ministry of Health and Family Welfare, Government of India. Annual report to the people on health 2014-15. Available from: http://www.mohfw.nic.in/.pdf. Accessed on 9 December 2016.

Downloads

Published

2020-11-23

Issue

Section

Original Research Articles