DOI: http://dx.doi.org/10.18203/2349-3933.ijam20210274

Systemic sclerosis: a rare presentation

Elvi Aprillia Karamoy, Jason Raymond Hotama, Ketut Suryana, Novitasari .

Abstract


Systemic sclerosis or so called scleroderma is an uncommon autoimmune inflammatory and fibrotic connective tissue disease involving multiple organs. The etiology of systemic sclerosis is currently unknown and its pathogenesis is only partially understood. Skin thickening and Raynaud’s phenomenon are the most common symptoms. Although systemic sclerosis is uncommon, it is associated with high morbidity and mortality. In this report, we present a case of a-43-year-old man with the complaint of weakness, tightening of the skin over the fingers, tingling in the soles of feet, nausea and significant weight loss. Laboratory examinations revealed positive ANA test, but negative anti topoisomerase I (anti-Scl-70), and anticentromere antibody.

Keywords


Systemic sclerosis, Scleroderma, Sclerodactyly, Skin thickening, Autoimmune

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