Comparative study of clinical profile of patients with stroke in diabetic and non-diabetic patients admitted to SIMS Shivamogga
DOI:
https://doi.org/10.18203/2349-3933.ijam20205474Keywords:
Stroke, Diabetic, HemorrhageAbstract
Background: Diabetes mellitus is one of the major risk factor for stroke. Stroke in diabetic patients is different from stroke in non-diabetics in many aspects. This study was carried out to with the aim to compare the clinical profile of patients with diabetic non-diabetic stroke, and its outcome. The objective of the study was to compare the clinical profile of stroke in diabetics and non-diabetics.
Methods: The present study is a prospective case control observational study, carried out at Shivamogga Institute of Medical Sciences, Shivamogga. 100 patients with stroke were enrolled (out of which 50 patients were diabetic or found to have diabetes during hospital stay, and 50 were non-diabetic stroke patients). Other risk factors, clinical presentation and the pattern of stroke were evaluated.
Results: The mean age in diabetic stroke patients was 56±9.93. and in non-diabetic stroke patients was 59.92±13.26. Percentage of male population in both groups were higher. Stroke patients in both study groups presented with history of motor weakness as their most common presenting complaint. 69% of diabetic patients had past history of hypertension compared to 21% in non-diabetic group. The mean blood sugar on admission was higher in diabetic group (221.87±76.16) compared with in non-diabetic group (133.12±44.68). Diabetic patients had greater percentage of ischemic stroke (65%) as compared to non-diabetic patients (33%). Hemorrhages were less in diabetic stroke patients (35%) as compared to non-diabetics (67%).
Conclusions: Stroke in diabetic patients has a specific clinical pattern and a poor prognosis, which emphasizes the need for early diagnosis and treatment of every case of diabetes.
References
Smith WS, Johnston C, Easton JD, Kasper DL. Harrison‟s Principle of internal medicine,17th Edn Volume 2, Mc Graw Hill Medical Publishing Division. 2008.
Goldstein M, Barnett HJM, Orgogozo JM, Sartorius N. Recommendations on stroke prevention, diagnosis, and therapy. Report of the WHO Task Force on Stroke and other Cerebrovascular Disorders. Stroke. 1989;20:1407-31.
Samuels MA, Ropper AH. Adams and Victors principles of neurology. 9thEdn. McGraw Hill Publishing Division. 2009:821-917.
Bell DS. Stroke in the diabetic patient. Diabetes Care. 1994;17:213-19.
Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC. Stress hyperglycemia and prognosis in non diabetic and diabetic patients. Stroke. 2001;32:2426-32.
Van Kooten F, Hoogerbrugge N, Naarding P, Koudstall PJ. Hyperglycemia in the 94 acute phase of stroke is not caused by stress. Stroke. 1993;24:1129-32.
Gray CS, Taylor R, French JM. The prognostic value of stress hyperglycemia and previously unrecognized diabetes mellitus in acute stroke. Diabetic Med. 1987;4:237.
Jorgensen HS, Nakayama H, Raaschou HO, Gam J, Oslen TS. Silent infarction in acute stroke patients prevelances, localization, risk factors and clinical signifances. The Copenhagen Stroke Study. Strok.e 1994;25:97-104.
McCall AL. The impact of diabetes on the CNS. Diabetes. 1992;41:557-70.
Kiessla BM, Khoury J, Kleindorfer D, Woo D, Schneider A, Alwell K, et al. Epidemiology of ischemic stroke in patientswith diabetes: the greater Cincinnati/Northern Kentucky Stroke Study. Diabetes Care. 2005;28:355-9.
Fuentes B, Castillo J, Jose BS, Leira R, Serena J, Vivancos J et al. The prognostic value of capillary glucose levels in acute stroke. Stroke. 2009;40:562-68.
Megherbi SE, Milan C, Minier D, Couvreur G, Osseby GV, Tilling K et al. Association between diabetes and stroke subtype on survival and functional outcome 3 months after stroke. Stroke. 2003;34:688.
