Factors responsible for low serum vitamin-D levels in type-2 diabetes mellitus females: a cross-sectional study

Authors

  • E. Dinesh Ragav Department of General Medicine, Sri Sathyasai Medical College and Research Institute, Ammapettai, Chengalpettu, Tamil Nadu, India
  • Arthi P. S. Department of General Medicine, Sri Sathyasai Medical College and Research Institute, Ammapettai, Chengalpettu, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20211469

Keywords:

Female type-2 diabetes, FBS, PPBS, Serum vitamin-D

Abstract

Background: Diabetes mellitus are a group of disorders as a result of reduced insulin secretion, insulin resistance, and increased glucose production and many more unknown etiologies. As compared to diabetic non-obese, diabetic obese individuals have an increased chance of 13.5 % in developing diabetic complications. Many diabetic patients are found to be vitamin-D deficient and its role in insulin regulation is being studied in many studies. Thus, diabetic complications and vitamin-D deficiency are likely to be developed in obese diabetic females.

Methods: Type-2 diabetic females from 30 years to 60 years, attending in medicine as out-patient and female type-2 diabetes patients admitted in medical ward of RRMCH were assessed clinically. Parameters such as anthropometric measurements, weight, height, waist-hip ratio, tested for serum levels vitamin-D including other relevant investigations related to diabetes were done. Totally, 156 patients were assessed.

Results: Assessment of 156 patients are as follows, 48.47±9.56years was the mean age of this study group. SD: 5.10±4.36 years is the mean diabetic duration of this study population. 0.98 was the mean waist-hip ratio. 98.93 cm was the mean waist circumference. 24.97 was the mean BMI. Mean fasting blood sugar (FBS) and post-prandial glucose test (PPBS) were: 202.73 mg/dl, 280.99 mg/dl respectively, 9.33% was the mean HbA1C. Majority of the females with type-2 diabetes (92.5%) had low levels of serum vitamin-D. 16.19 ng/ml was the mean serum vitamin-D levels. lower levels of serum vitamin-D were significantly associated with diabetic duration (p=0.082+), poor glycaemic control (p<0.001**) and increased BMI (p=0.011*).

Conclusions: Majority of the females with type-2 diabetes mellitus were with waist-hip ratio more than 0.8 and Waist circumference more than 80 cm. Most of the study population had poor diabetic control. Lower levels of serum vitamin-D were found in almost all females with type-2 diabetes mellitus (92.5 %) and the most likely risk factor being obesity and poor glycaemic control as a conclusion of this study.

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Author Biographies

E. Dinesh Ragav, Department of General Medicine, Sri Sathyasai Medical College and Research Institute, Ammapettai, Chengalpettu, Tamil Nadu, India

Assistant professor,

Department of general medicine,

Sri sathyasai medical college,

Ammapettai, thiruporur-guduvancherry road,

chengalpetu district,

tamil nadu-603108

Arthi P. S., Department of General Medicine, Sri Sathyasai Medical College and Research Institute, Ammapettai, Chengalpettu, Tamil Nadu, India

Assistant professor,

Department of general medicine,

Sri sathyasai medical college,

Ammapettai, thiruporur-guduvancherry road,

chengalpetu district,

tamil nadu-603108

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Published

2021-04-22

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Original Research Articles