Timing methylprednisolone pulse therapy in COVID-19 infection-finding the sweet spot: a case series


  • Anupam Kumar Department of Internal Medicine and Endocrinology, Command Hospital (SC), Pune, Maharashtra, India
  • Suhail Singh Department of Internal Medicine, Command Hospital (SC), Pune, Maharashtra, India
  • Vikas Sherawat Department of Internal Medicine, Command Hospital (SC), Pune, Maharashtra, India




Corticosteroid, COVID-19, Methyl prednisolone, SARS-CoV-2


Steroid therapy has been proven beneficial in the treatment of SARS-CoV2 in various trials all around the world. However, the dosing and timing of this therapy are crucial and still under debate. Studies exist regarding the use of Pulse IV therapy of steroids in this illness, but it has still not been widely used and accepted throughout the world. Here we describe four cases of SARS-CoV2 who presented to a tertiary care center in India within the first week of illness, with moderate to severe disease activity. These patients were treated with Pulse doses of intravenous MethylPrednisolone. All four patients showed positive outcomes in terms of oxygen requirement and early recovery.


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