Evaluation of COVID-19 patients requiring oxygen therapy in a tertiary care teaching hospital

Priti Dave; Gargee M. Pore; V. P. Singh; Supriya S. Barsode

doi:10.18203/2349-3933.ijam20214522

Authors

Priti Dave Department of Medicine, Bharati Hospital and Research Centre, Pune, Maharashtra, India
Gargee M. Pore Department of Medicine, Bharati Hospital and Research Centre, Pune, Maharashtra, India
V. P. Singh Department of Medicine, Bharati Hospital and Research Centre, Pune, Maharashtra, India
Supriya S. Barsode Department of Medicine, Bharati Hospital and Research Centre, Pune, Maharashtra, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20214522

Keywords:

COVID-19, Clinical features, LDH, CRP, D-dimer, SpO2

Abstract

Background: COVID-19 disease is a public health emergency and declared as a pandemic in March 2020 by World Health Organization (WHO). Our aim was to study the clinical features, laboratory profile and outcome of COVID-19 patients needing oxygen therapy.

Methods: All patients diagnosed to be having COVID-19 and SpO₂less than 94% on admission were included in the study. Detailed history, systemic examination and investigations were done and data was analyzed.

Results: Out of 100 patients studied, 66% were males and 34% were females. Comorbidity was seen in 83% of cases, predominantly hypertension (30%) followed by diabetes mellitus (27%) and ischemic heart disease IHD (11%). Most common presenting complaints were breathlessness (84%) followed by dry cough (63%) and fever (48%). Mean values of absolute counts of neutrophils, lymphocytes, eosinophils and basophils were 4,835 cells/cu.mm, 1,332 cells/cumm, 66 cells/cumm and 86.5 cells/cumm respectively. Serum C-reactive protein (CRP) was raised in 90%, lactate dehydrogenase (LDH) in 96% and D-dimer in 64 % of cases on admission. Incidence of happy hypoxia was 16%. Mortality in our study was 2%. Greater the values of serum CRP, LDH, ferritin, lesser was the SpO₂ of patients and greater the oxygen requirement. However no such correlation was found between D-Dimer and SpO₂ of patients and their oxygen requirement.

Conclusions: COVID-19 has varied presentations. The most common comorbidity was hypertension followed by diabetes mellitus. Serum inflammatory markers are raised in COVID disease. Eosinopenia can be a pointer towards COVID disease. One should be aware of the entity happy hypoxia seen in these patients.

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Author Biography

Priti Dave, Department of Medicine, Bharati Hospital and Research Centre, Pune, Maharashtra, India

Professor, Medicine department

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