Study of cardiac manifestations in hypothyroid patients admitted in tertiary care centre
Keywords:Thyroid, Hypothyroidism, Thyroid stimulating hormone, Electrocardiogram, Echocardiography
Background: Hypothyroidism is the most common pathological hormone deficiency. To study various cardiac manifestations in overt and subclinical hypothyroidism.
Methods: The cross-sectional analytic study is carried out on 60 patients of hypothyroid subjects in indoor facility of general medicine department in SMIMER hospital.
Results: This study shows positive correlation between thyroid stimulating hormone (TSH) level, electrocardiogram (ECG) and echocardiographic findings. In this study, there is female predominance, ECG findings most commonly suggestive of sinus bradycardia and ECHO findings are most commonly suggestive of diastolic dysfunction with pericardial effusion.
Conclusions: The early recognition and early initiation of treatment of hypothyroidism may helpful to lowering heart changes as hypothyroidism is reversible cause for cardiac manifestation.
Davis FT, Larsen RP. Hypothyroidism and thyroiditis 10th ed. Chapter 12. In: William’s text book of endocrinology, Larsen Melmed, Polonsky, eds. Philadelphia: Saunders. 2003;423-55.
Klein I. Endocrine disorder and cardiovascular diseases. 8th ed. Chapter 81. In: Braunwald’s heart disease. Philadelphia: Saunders. 2008;432-49.
Klein I, Danzi S. Thyroid disease and heart. Circulation. 2007;116:1725-35.
Fadel. Hyperthyroid heart disease. Clinical Cardiology. 2000;23:402-8.
Poliker R. The thyroid and the heart. Circulation. 1993;87:1435-41.
Boindi B. Effects of subclinical Thyroid Dysfunction on the heart. Annuals of Internal Medicine. 2002;137:904-14.
Verma R. Heart in hypothyroidism. JAPI. 1996;44:390-3.
Hardisty. Pericardial effusion in hypothyroidism. Clin Endocrinol. 1980;13(4):349-54.
Rawat. An echocardiographic study of cardiac changes in hypothyroidism and the response to treatment. Kathmandu University Medical Journal. 2003;2(3):182-7.
Verma R. Heart in hypothyroidism – an echocardiographic study. J Assoc Phy India. 1996;44:390-2.
Gupta. Echocardiographic changes and alterations in lipid profile in cases of subclinical and overt hypothyroidism. The Journal of the Association of Physicians of India. 1996;44(8):546,551-3.
Al-Farttoosi. Cardiovascular Manifestations of Primary Hypothyroidism. The Iraqi Postgraduate Medical Journal. 2010;9(2):113-9.