DOI: https://dx.doi.org/10.18203/2349-3933.ijam20220793
Published: 2022-03-24

Colchicine for pericarditis due to COVID-19: a case report

Parth Patel, Sudhendu Patel, Vidhi Shah

Abstract


The pericardium is a fibroelastic sac made up of visceral and parietal layers separated by a (potential) space, the pericardial cavity.The most troublesome complication of acute pericarditis is the development of recurrent episodes of pericardial inflammation, occurring in 15% to 32% of cases. Therapeutic modalities are nonspecific and include non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. Here we present a case of a patient presenting with pericarditis due to COVID-19. He was successfully treated with colchicine. To our knowledge acute pericarditis due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) might be an under diagnosed condition in this pandemic. We want to share our findings, given the urgent need for different diagnostic and therapeutic strategies in order to better manage COVID-19 patients, and diminish the SARS-CoV-2 complications.


Keywords


COVID-19, Pericarditis, Colchicine

Full Text:

PDF

References


Acute pericarditis: Treatment and prognosis. Available at: https://www.uptodate.com/contents/acute-pericarditis-treatment-and prognosis/print. Accessed on 24 December 2021.

Spodick DH. Diseases of the pericardium. In: Parmley WW, Chatterjee K, editors. Cardiology. Philadelphia, Pa: JB Lippincott. 1992;1-34.

Carmichael DB, Sprague HB, Wyman SM. Acute nonspecific pericarditis: clinical laboratory and follow-up considerations. Circulation. 1951;3:321-31.

Clementy J, Jambert H, Dallarrhio M. Les pericarditis aigues recidivantes:20 observations. Arch Mal Coeur. 1979;72:857-61.

Connolly DC, Burchell HB. Pericarditis: a ten-year survey. Am J Cardiol. 1961;7:7-14.

Engle MA. Pericardiology and allied syndromes. In: Reddy PS, editor. Pericardial Disease. New York, NY: Raven Press. 1982;313-23.

Robinson J, Bergden W. Recurrent pericarditis. BMJ. 1968;2:272-5.

Miller JI, Mansour KA, Hatcher CR. Pericardiectomy: current indications, concepts, and results in a university center. Ann Thorac Surg. 1982;84:40-5.

Spodick DH. The Pericardium: A Comprehensive Textbook. New York, NY: Marcel Dekker. 1997;422-32.

Adler Y, Zandman-Godard G, Ravid M, Avidan B, Zemer D, Ehrenfeld M, et al. Usefulness of colchicine in preventing recurrences of pericarditis. Am J Cardiol. 1994;783:916-7.

Wright DG, Wolff SM, Fauci AS, Alling DW. Efficacy of intermittent colchicine therapy in familial Mediterranean fever. Ann Intern Med. 1977;86:162-5.

Adler Y, Charron P, Imazio M, Badano L, Barón-Esquivias G, Bogaert J, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC) Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2015;36:2921.

Multicenter collaboration group of Department of Science and Technology of Guangdong Province and Health Commission of Guangdong Province for chloroquine in the treatment of novel coronavirus pneumonia. [Expert consensus on chloroquine phosphate for the treatment of novel coronavirus pneumonia]. Zhonghua Jie He He Hu Xi Za Zhi. 2020;43(3):185-8.

Maestroni S, Di Corato PR, Cumetti D, Chiara DB, Ghidoni S, Prisacaru L, et al.Recurrent pericarditis: autoimmune or autoinflammatory? Autoimmun Rev. 2012;12:60.

Cremer PC, Kumar A, Kontzias A, Tan CD, Rodriguez ER, Imazio M, et al. Complicated pericarditis: understanding risk factors and pathophysiology to inform imaging and treatment. J Am Coll Cardiol. 2016;68:2311-28.

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-9.

Li K, Wu J, Wu F, Guo D, Chen L, Fang Z, et al. The clinical and chest CT features associated with severe and critical COVID-19 pneumonia. Invest Radiol. 2020;55(6):327-31.

Zhu J, Ji P, Pang J, Zhong Z, Li H, He C, Zhang J, Zhao C. Clinical characteristics of 3062 COVID-19 patients: A meta-analysis. J Med Virol. 2020;92(10):1902-14.

Hu H, Ma F, Wei X, Fang Y. Coronavirus fulminant myocarditis treated with glucocorticoid and human immunoglobulin. Eur Heart J. 2021;42(2):206.

Han Y. Initial COVID-19 affecting cardiac patients in China. Eur Heart J. 2020;41:1719.

Inciardi RM, Lupi L, Zaccone G, Italia L, Raffo M, Tomasoni D, et al. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020;5(7):819-24.

Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802-10.

Dabbagh MF, Aurora L, D'Souza P, Weinmann AJ, Bhargava P, Basir MB. Cardiac Tamponade Secondary to COVID-19. JACC Case Rep. 2020;2(9):1326-30.

Fancello L, Monteil S, Popgeorgiev N, Rivet R, Gouriet F, Fournier P, et al. Viral communities associated with human pericardial fluids in idiopathic pericarditis. PLoS One. 2014;9:e93367.

Kytö V, Sipilä J, Rautava P. Clinical profile and influences on outcomes in patients hospitalized for acute pericarditis. Circulation. 2014;130:1601-6.

Koos R, Schröder J, Kühl HP. Acute viral pericarditis without typical electrocardiographic changes assessed by cardiac magnetic resonance imaging. Eur Heart J. 2009;30:2844.

Bayes- Genis A, Adler Y, de Luna AB. Colchicine in pericarditis. Eur Heart J. 2017;38:1706-9.

Gandolfini I, Delsante M, Fiaccadori E, Zaza G, Manenti L, Degli Antoni A, et al. COVID-19 in kidney transplant recipients. Am J Transplant. 2020;20(7):1941-3.

Perricone C, Triggianese P, Bartoloni E, Cafaro G, Bonifacio AF, Bursi R, Perricone R, Gerli R. The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19. J Autoimmun. 2020;111:102468.

Zhang W, Zhao Y, Zhang F. The use of anti- inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): the perspectives of clinical immunologists from China. Clin Immunol. 2020;214:108393.