DOI: https://dx.doi.org/10.18203/2349-3933.ijam20220789
Published: 2022-03-24

Fatal systemic reactions, concurrent of anaphylaxis and systemic toxic reactions to hymenoptera-sting

Ketut Suryana, Dwijo Anargha Sindhughosa

Abstract


Hymenoptera-sting can cause localized and systemic reactions (SR). SRs such as anaphylaxis and systemic toxic reactions (STR). It is estimated to occur in 3% of adults and can be life-threatening. Diagnosis is based on clinical manifestations, previous of allergic history, IgE-mediated confirmation and the offending insect identification. Anaphylaxis patients should immediately receive adrenaline intramuscularly, emergency medical attention and other supporting treatment. We report a 36-year-old man with fatal SRs, concurrent of anaphylaxis and systemic toxic reaction due to multiple hymenoptera-stings. 

 


Keywords


Hymenoptera-sting, Anaphylaxis reaction, Systemic toxic reaction, Organ failure

Full Text:

PDF

References


Unal D. Hymenoptera venom anaphylaxis. J Immunol Clin Res. 2018;5(1):1047.

Cichocka-Jarosz E. Hymenoptera venom allergy in humans. Folia Me Cracov. 2012;52(3-4):43-60.

Betten DP, Richardson WH, Tong TC. Massive honey bee envenomation-induced rhabdomyolysis in an adolescent. Pediatrics. 2006;117(1):231-5.

Fonteque JH, Mendes RP, Souza AF. Systemic toxic reaction due to multiple honeybee stings in equine: Case report. Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 2018;70:767-72.

Ou WF, Huang WH, Chiu HF, Mao YC, Wen MC, Chen CH et al. Clinical manifestation of multiple wasp stings with details of whole transcriptome analysis: Two case reports. Medicine (Baltimore). 2021;100(4):e24492.

Ittyachen AM, Abdulla S, Anwarsha RF. Multi-organ dysfunction secondary to severe wasp envenomation. Int J Emerg Med. 2015;8:6.

Daher EF, Silva Junior GB, Bezerra GP, dkk. Acute renal failure after massive honeybee stings. Rev Inst Med Trop São Paulo. 2003;45(1):45-50.

Bilò MB, Tontini C, Martini M, Corsi A, Agolini S, Antonicelli L. Clinical aspects of hymenoptera venom allergy and venom immunotherapy. Eur Ann Allergy Clin Immunol. 2019;51(6):244-58.

Fehr D, Micaletto S, Moehr T, Schmid-Grendelmeier P. Risk factors for severe systemic sting reactions in wasp (Vespula spp.) and honeybee (Apis mellifera) venom allergic patients. Clin Transl Allergy. 2019;9:54.

Stoevesandt J, Sturm GJ, Bonadonna P, Oude Elberink JNG, Trautmann A. Risk factors and indicators of severe systemic insect sting reactions. Allergy. 2020;75(3):535-45.

Prado M, Quirós D, Lomonte B. Mortality due to Hymenoptera stings in Costa Rica, 1985-2006. Rev Panam Salud Publica. 2009;25(5):389-93.

Pramanik S, Banerjee S. Wasp stings with multisystem dysfunction. Indian Pediatr. 2007;44(10):788-90.

Przybilla B, Ruëff F. Insect stings: clinical features and management. Dtsch Arztebl Int. 2012;109(13):238-48.

Yao X, Wang J, Liu B. A case report of anaphylactic shock induced by cisatracurium. Arch Clin Med Case Rep. 2019;3(5):285-8.

Peavy R, Metcalfe D. Understanding the mechanisms of anaphylaxis. Curr Opin Allergy Clin Immunol. 2008;8(4):310-5.

Sreevastava L, Tarneja S. Anaphylactic reaction: An overview. MJAFI. 2003;59:53-6.

Jimenez-Rodriguez TW, Garcia-Neuer M, Alenazy LA, Castells M. Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers. J Asthma Allergy. 2018;11:121-42.

imons FE, Ardusso LR, Bilò MB, Dimov V, Ebisawa M, El-Gamal YM et al. World Allergy Organization. 2012 Update: World Allergy Organization Guidelines for the assessment and management of anaphylaxis. Curr Opin Allergy Clin Immunol. 2012;12(4):389-99.

Sampson HA, Muñoz-Furlong A, Campbell RL, Adkinson NF Jr, Bock SA, Branum A et al. Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol. 2006;117(2):391-7.

Muraro A, Roberts G, Worm M, Bilò MB, Brockow K, Fernández Rivas M et al. Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology. Allergy. 2014;69(8):1026-45.

Dodd A, Hughes A, Sargant N, Whyte AF, Soar J, Turner PJ. Evidence update for the treatment of anaphylaxis. Resuscitation. 2021;163:86-96.

Shaker MS, Wallace DV, Golden DBK, et al. Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis. J Allergy Clin Immunol. 2020;145(4):1082-123.

Ribeiro, Maria Luiza Kraft Köhler, Chong, Herberto José and Rosario, Nelson AugustoDiagnosis and treatment of anaphylaxis: there is an urgent need to implement the use of guidelines. Einstein (São Paulo). 2017;15:500-6.

Brown SG, Mullins RJ, Gold MS. Anaphylaxis: diagnosis and management. Med J Aust. 2006;185(5):283-9.

Radhakrishnan H. Acute kidney injury and rhabdomyolysis due to multiple wasp stings. Indian J Crit Care Med. 2014;18(7):470-2.

Toledo L, Moore D, Caixeta D. Multiple bee stings, multiple organs involved: a case report. Rev Soc Bras Med Trop. 2018;51(4):560-2.

Nandi M, Sarker S. Acute kidney injury following multiple wasp stings. Pediatr Nephrol. 2012;27:2315-7.

Mejía Vélez G. Acute renal failure due to multiple stings by Africanized bees. Report on 43 cases. Nefrologia. 2010;30(5):531-8.