Published: 2022-03-24

A study of correlation between prevalence of pulmonary artery hypertension with severity of bronchiectasis

Sachin Vidyasagar, Natesh Ganesan, Gangadharan Vadivelu


Background: Pulmonary artery hypertension (PAH) dreadful complication in bronchiectasis. The 6th world symposium on pulmonary hypertension have taken mPAP of 20 mmHg as normal. Not much studies have been done based on the current cut off values, so we have incorporated values based on the new guidelines and made following observations.

Methods: This study was designed as an observational cross-sectional study consisting of 27 patients, who were admitted in Pulmonary medicine department.

Results: Out of 27 study subjects 15 were female’s and 12 were males. It was found that 70.3% had less than 5 segments involved and 29.6% had more than 5 segments involved. Mean value of PAH was 34.48±18.06 mmHg. Analysis showed a significant correlation (r=0.67) between number of segments involved and incidence of pulmonary hypertension.

Conclusions: It is essential to evaluate the cardiac status of bronchiectasis patients at the time of diagnosis as cardiac manifestations are one of the dreadful complications. 


Chronic lung diseases, PAH, Cardiac evaluation

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Wijeratne DT, Lajkosz K, Brogly SB, Lougheed MD, Jiang L, Housin A et al. Increasing incidence and prevalence of World Health Organization groups 1 to 4 pulmonary hypertension: a population-based cohort study in Ontario, Canada. Circulation: Cardiovascular Quality and Outcomes. 2018;11(2): e003973.

Simonneau G, Montani D, Celermajer DS, Denton CP, Gatzoulis MA, Krowka M et al. Haemodynamic definitions and updated clinical classification of pulmonary hypertension. Eur Respiratory J. 2019;53(1).

Croftons and Douglas’s Textbook of Respiratory Diseases /5th Edition/Chapter 28. 2000;794-828.

Sylvester JT, Shimoda LA, Aaronson PI, Ward JP. Hypoxic Pulmonary vasoconstriction Physiol Rev. 2012;92(1):367-520.

Lee Al, Button BM, Ellis S, Holland AE. Clinical determinants of the 6-Minute Walk Test in bronchiectasis. Respiratory Med. 2009;103:780-5.

Miyamoto S, Nagaya N, Satoh T. Clinical correlates and Prognostic significance of Six-minute walk test in patients with primary pulmonary hypertension, comparison with cardiopulmonary exercise testing. Am J Respir Crit Care Med. 2000;161:487-92.

Devaraj A, Wells AU, Meister MG, Corte TJ, Wort SJ, Hansell DM. Detection of pulmonary hypertension with multidetector CT and echocardiography alone and in combination. Radiology. 2010;254(2):609-16.

Alhamad EH, Al-Boukai AA, Al-Kassimi FA, Alfaleh HF, Alshamiri MQ, Alzeer AH et al. Prediction of pulmonary hypertension in patients with or without interstitial lung disease: reliability of CT findings. Radiology. 2011;260(3):875-83.