Delayed diagnosis of disseminated tuberculosis in pregnancy: a case report

Authors

  • Sushmita Vinod Department of Respiratory Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Gangadharan Vadivelu Department of Respiratory Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Anbumaran Parivakkam Mani Department of Respiratory Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20221367

Keywords:

Tuberculoma, Miliary TB, Ante-natal

Abstract

Miliary tuberculosis (TB) is a lethal form of TB, if left untreated. Miliary TB accounts for <2% of all cases of TB in immunocompetent individuals. Intracranial tuberculoma is a rare manifestation of Mycobacterium tuberculosis (MTB), seen in only 1% of TB patients. It can occur as single or multiple lesions, most commonly located in the frontal and parietal lobes. Clinical features mimic that of any space-occupying lesion in the brain. In pregnant women, diagnosis of TB may be delayed by the non-specific nature of early symptoms and because they are often attributed to pregnancy.Here we report one such case where the diagnosis of TB was delayed due to the non-specific nature of her symptoms in ante-natal period.

References

Loto OM, Awowole I: Tuberculosis in pregnancy: a review. J Pregnancy. 2012;2012:379271.

Sahn SA, Neff TA. Miliary tuberculosis. Am J Med. 1974;56:495-505.

Sharma SK, Mohan A. Disseminated and miliary tuberculosis. In: Sharma SK, Mohan A, eds. Tuberculosis. 2nd ed. New Delhi: Jaypee Brothers; 2009: 493-518.

Baker SK, Glassroth J. Miliary tuberculosis. In: Rom WN, Garay SM, eds. Tuberculosis. Philadelphia: Lippincott Williams and Wilkins; 2004: 427-444.

Divinagracia R, Harris HW. Miliary tuberculosis. In: Schlossberg D, eds. Tuberculosis and Non-tuberculous Mycobacterial Infection. Philadelphia: WB Saunders; 1999: 271-284.

Schaller MA, Wicke F, Foerch C, Weidauer S. Central nervous system tuberculosis: etiology, clinical manifestations and neuroradiological features. Clin Neuroradiol. 2019;29(1):3-18.

Phypers M, Harris T, Power C. CNS tuberculosis: a longitudinal analysis of epidemiological and clinical features. Int J Tuberc Lung Dis. 2006;10(1):99-103.

Wilkinson RJ, Rohlwink U, Misra UK, Crevel R, Mai NTH, Dooley KE. Tuberculous Meningitis International Research Consortium Tuberculous meningitis. Nat Rev Neurol. 2017;13(10):581-98.

Henry M, Holzman RS. Tuberculosis of the brain, meninges and spinal cord. In: Rom WN, Garay SM, eds. Tuberculosis. Philadelphia: Lippincot Williams and Wilkins; 2004: 445 464.

Radhakrishnan K, Kishore A, Mathurnath PS. Neurological tuberculosis. In: Sharma SK, Mohan A, editors. Tuberculosis. New Delhi: Jaypee Brothers; 2009: 209 228.

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Published

2022-05-24

Issue

Section

Case Reports