Comparative study of prevalence of hypothyroidism in cirrhotic patients and normal individuals

Authors

  • Harish Charpota District Hospital, Banswara, Rajasthan, India
  • Rajesh Meena Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India
  • O. P. Meena Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India
  • Gurdeep Kaur Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India
  • Deepa Katara District Hospital, Banswara, Rajasthan, India
  • Atul Meena Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20221705

Keywords:

Liver disease, Alcoholism, Serum albumin, Hypothyroidism

Abstract

Background: Alcoholic cirrhosis has worse prognosis than primary billiary cirrhosis and cirrhosis due to hepatitis. The risk of death due to all cause is increased 12-fold with cirrhosis. Alcoholic liver cirrhosis develops between 10-20% of individuals who drink heavily for a decade or more. Chronic hepatitis B is probably the most common cause of cirrhosis worldwide. The aim and objective of this study was to compare the prevalence of hypothyroidism between cirrhotic patients and normal healthy individuals.

Methods: The present study constitutes of 50 patients with cirrhosis of liver who met our inclusion criteria. They were selected from the patients admitted in medical wards and gastroenterology ward of RNT medical college, Udaipur.

Results: Majority of patients were of serum albumin level class III about 67%. Increased TSH level as compare to level of serum albumin in cirrhotic patients. When serum albumin level decreases then percent of TSH level increases. Majority of patients were from serum bilirubin class III (71%). Majority were from serum bilirubin class III about 70%.

Conclusions: All cirrhotic patients should undergo for evaluation of endocrinological evaluation as these patients are associated with development of hypothyroidism. After diagnosis the treatment of endocrinological disorder especially hypothyroidism may increase survival.

Author Biographies

Harish Charpota, District Hospital, Banswara, Rajasthan, India

Sr. Medical Officer, Dist. Hospital, Banswara

Rajesh Meena, Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India

Assistant Professor, Department of General Medicine, RNT Medical College, Udaipur

O. P. Meena, Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India

Sr. Professor, Department of General Medicine, RNT Medical College, Udaipur

Gurdeep Kaur, Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India

Sr. Professor and HOD,

Department of General Medicine,

RNT Medical College, Udaipur

Deepa Katara, District Hospital, Banswara, Rajasthan, India

JOS, District Hospital, Banswara

Atul Meena, Department of Medicine, RNT Medical College, Udaipur, Rajasthan, India

Junior Resident, Department of General Medicine, RNT Medical College, Udaipur

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Published

2022-06-27

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Original Research Articles