An interesting case of anemia with jaundice

Authors

  • Aishwarya Saravanan Department of General Medicine, Saveetha Medical College Hospital, Chennai, Tamil Nadu, India
  • Mariraj Indiran Department of General Medicine, Saveetha Medical College Hospital, Chennai, Tamil Nadu, India
  • Prasanna Karthik Suthakaran Department of General Medicine, Saveetha Medical College Hospital, Chennai, Tamil Nadu, India
  • Jagadeesan Mohanan Associate Professor Department of General Medicine Saveetha Medical College Hospital, Thandalam, Chennai, Tamilnadu, India
  • Mahendrakumar Kaappan Department of General Medicine, Saveetha Medical College Hospital, Chennai, Tamil Nadu, India
  • Kannan Rajendran Department of General Medicine, Saveetha Medical College Hospital, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20221364

Keywords:

Hemoglobin E disease, Hemoglobinopathies, HbE Thalassemia

Abstract

Hemoglobinopathies are haematalogical disorders that afflict millions of individuals worldwide. HbE is a hemoglobin variation caused by a mutation in the β globin gene that results in the substitution of glutamic acid for lysine at position 26 of the β globin gene. Hemoglobin (Hb) synthesis abnormalities are among the most prevalent inherited disorders. They can be quantitative (thalassemia syndrome) or qualitative (variant HbS). Hemoglobin E (HbE) is the second most common hemoglobin variation after hemoglobin S (HbS).

References

Jain D, Gupta SK, Singh T. Hemoglobin E disease with concomitant tuberculosis. Indian Journal of Pathology and Microbiology. 2008;51:570.

Vichinsky E. Hemoglobin E Syndromes. American Society of Hematology. 2007;(1):79-83.

Patne SCU, Shukla J. Hemoglobin E disorders in Eastern Uttar Pradesh. Indian Journal of Pathology and Microbiology. 2000;52(1):110-2.

Mias DD, Gulberson RD, Keren DF. The Range of Hemoglobin A2 in Hemoglobin E Heterozygotes as Determined by Capillary Electrophoresis. American Journal of Clinical Pathology. 2009;132:34-8.

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Published

2022-05-24

Issue

Section

Case Reports