A study on association of serum magnesium, serum uric acid levels and microalbuminuria in patients with type 2 diabetes mellitus


  • Shubham Jain Department of Medicine, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India
  • Birata Debbarma Department of Medicine, Tripura Medical College and Dr. BRAM Teaching Hopsital, Agartala, Tripura, India
  • Devdas Rai Department of Medicine, A. J. Institute of Medical Sciences, Manguluru, Karnataka, India




Magnesium, Uric acid, Microalbuminuria, Type 2 diabetes


Background: Microalbuminuria is multifactorial and it is an important marker for diabetic nephropathy. The aim of the study was to assess the incidence and association of serum magnesium levels, serum uric acid levels and microalbuminuria in patients with type 2 DM.

Methods: This study was a cross-sectional study conducted for a period of 2 years from October 2015 to September 2017, where the patients diagnosed as type 2 DM admitted in AJIMS were taken up for the study. All the patients’ blood sample was sent for estimation of serum magnesium, serum uric acid, FBS, PPBS, HBA1C and urine spot albumin:creatinine ratio.

Results:In our study, out of 100 patients with type 2 diabetes, 79 patients had microalbuminuria. Out of these, 83.3% (N=75) was having hypomagnesemia (p<0.000) associated with microalbuminuria. Hyperuricemia was seen in 63% (N=63) of the population but 79.4% (N=50) hyperuricemics were associated with microalbuminuria(p<0.000).

Conclusions:There was a significant microalbuminuria in patients with type 2 DM, with reduced serum Mg levels and elevated serum uric acid levels as compared with patients who had serum Mg and uric acid levels within the normal range. 


Author Biography

Shubham Jain, Department of Medicine, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India

Sr. resident, Medicine,


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Original Research Articles