A case of pituitary adenoma presenting with normal hormone levels
DOI:
https://doi.org/10.18203/2349-3933.ijam20222674Keywords:
Pituitary adenoma, Pituitary stalk tumor, HyperprolactinemiaAbstract
We report a case of pituitary adenoma with normal hormone levels in a 34-year-old female. She presented to OP with headache, milky discharge from nipples and secondary amenorrhea with transient loss of vision. Patient had hyperprolactinemia with normal levels of all other pituitary hormones. MRI revealed space occupying lesion in sellar and suprasellar region. Neurological consultation suggested Rathke’s cyst/ craniopharyngioma/ macroadenoma. Excised lesion was diagnosed as pituitary adenoma during histopathological analysis.
References
Endheim J. Uber einen Hypophysen tumor van ungewohnlichem Sitz. Beitr Pathol Anat. 1909;46:223-49.
Guerrero CA, Krayenbühl N, Husain M, Krisht AF. Ectopic suprasellar growth hormone-secreting pituitary adenoma: case report. Neurosurgery. 2007;61(4):E879.
Sharif-Alhoseini M, Rahimi-Movaghar V. Pituitary adenomas: a review. Journal of Injury and Violence Research. 2012;4:31.
Ntali G, Wass JA. Epidemiology, clinical presentation and diagnosis of non-functioning pituitary adenomas. Pituitary. 2018;21:111-18.
Ferrante E, Ferraroni M, Castrignano T, Menicatti L, Anagni M, Reimondo G et al. Non-functioning pituitary adenoma database: a useful resource to improve the clinical management of pituitary tumors. Eur J Endocrinol. 2006;155(6):823-9.
Kruse A, Astrup J, Gyldensted C, Cold GE. Hyperprolactinaemia in patients with pituitary adenomas. The pituitary stalk compression syndrome. Bri J Neurosurg. 1995;9(4):453-8.
Turkington RW, Underwood LE, Van Wyk JJ. Elevated serum prolactin levels after pituitary-stalk section in man. N Engl J Med. 1971;285(13):707-10.
Berkmann S, Fandino J, Müller B. Intraoperative MRI and endocrinological outcome of transsphenoidal surgery for non-functioning pituitary adenoma. Acta Neurochir. 2012;154:639-47.
Peter B, Nicholas TZ, Guillermo LC. Incidence and Management of Complications of Transsphenoidal Operation for Pituitary Adenomas. Neurosurgery. 1987;20(6):920-24.
Mazziotti G, Mancini T, Mormando M, De Menis E, Bianchi A, Doga M et al. High prevalence of radiological vertebral fractures in women with prolactin-secreting pituitary adenomas. Pituitary. 2011;14(4):299-306.
