Hoffman’s syndrome-a rare neurological presentation of hypothyroid myopathy

Authors

  • Tirumalasetty Sriharsha Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Chennai, Tamil Nadu, India
  • A. Arun Kumar Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Chennai, Tamil Nadu, India
  • Raghav Raj J. Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Chennai, Tamil Nadu, India
  • N. Monika Reddy Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Chennai, Tamil Nadu, India
  • Vikrannth V. Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Chennai, Tamil Nadu, India
  • Vinod Raghavan Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Chennai, Tamil Nadu, India
  • Kannan Rajendran Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20223029

Keywords:

Hoffman’s syndrome, Hypothyroidism, Pseudo hypertrophy

Abstract

Hoffman's syndrome is a rare form of hypothyroid myopathy, which causes proximal muscle weakness and pseudohypertrophy of muscles. It is a complication of untreated or uncontrolled Hypothyroidism.The neurological manifestations of hypothyroidism usually occur late in the course of disease. It is quite rare to present with neurological manifestations in the earlier stage of disease. Very few cases of Hoffman’s syndrome were reported from India. Here we report a case of 27-year-old male who presented to the medicine OPD with initial symptoms of proximal muscle weakness, fatigue and calf muscle hypertrophy. On further evaluation patient was found to have hypothyroid myopathy in the form of Hoffman’s syndrome.

References

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Published

2022-11-23

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Section

Case Reports