A case of stroke secondary to iron deficiency anemia in a young female patient

Authors

  • Devika Anilkumar Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
  • Manimekalai Periyasamy Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
  • Mullangi Chenchu Vinatha Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
  • J. Alex Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20223405

Keywords:

Iron deficiency anemia, Young ischemic stroke, Hypercoagulable state, Blood transfusions

Abstract

In this article, we are reporting a case of acute stroke that occurred in a young patient with iron deficiency anaemia (IDA). There are only a few cases where the association between IDA and stroke has been established. The possible mechanisms behind the relation between IDA and stroke are anaemic hypoxia-induced to the brain, hypercoagulable state secondary to IDA and thrombocytosis secondary to IDA. In this patient, all causes of stroke were ruled out except Iron deficiency anaemia which came out to be the reason for the stroke. A decrease in the amount of haemoglobin in the blood results in decreased oxygen supply to the brain, causing hypoxia to the brain. This, in turn, leads to ischemic stroke. Therefore, diagnosing anaemia in patients and starting treatment as early as possible is important.

References

Mehta J, Chapman S, Jayam-Trouth A, Kurukumbi M. Acute ischemic stroke secondary to iron deficiency anaemia: a case report. Case Rep Neurol Med. 2012;487080.

Maguire JL, deVeber G, Parkin PC. Association between iron-deficiency anemia and stroke in young children. Pediatrics. 2007;120:1053-7.

Chang Y-L, Hung S-H, Ling W, Lin H-C, Li H-C, Chung S-D. Association between ischemic stroke and iron deficiency anaemia: A Population-based Study. Plos One. 2013;8.

Killip JM, Bennett MD. Iron deficiency anaemia. Am Fam Phys. 2007;75:671-8.

Knizley WD. Iron deficiency anaemia, papilledema, thrombocytosis, and transient hemiparesis. Arch Int Med. 1972;129:483-6.

Alexander MB. Iron deficiency anaemia, thrombocytosis, and cerebrovascular accident. Southern Med J. 1983;76:662-3.

Hartfield DS, Lowry NJ, Keene DL, Yager JY. Iron deficiency: a cause of stroke in infants and children. Pediatr Neurol. 1997;16:50-3.

Akins PT, Glenn S, Nemeth PM, Derdeyn CP. Carotid artery thrombus associated with severe iron-deficiency anemia and thrombocytosis. Stroke. 1996;27:1002-5.

Caglayan HZB, Nazliel B, Irkec C, Dumlu A, Filiz M, Ates MP. Iron-deficiency anaemia leading to transient ischemic attacks due to intraluminal carotid artery thrombus. Case Rep Neurol Med. 2013;813415.

Huang I-C, Chen L, Meng W-C, Weng T. The influence of anaemia on clinical presentation and outcome of patients with first-ever atherosclerosis-related ischemic stroke. J Clin Neurosci. 2009;16:645-95.

Downloads

Published

2022-12-27

Issue

Section

Case Reports