Orbital apex syndrome due to scopulariopsis: a rare case report
DOI:
https://doi.org/10.18203/2349-3933.ijam20150569Keywords:
Scopulariopsis, Orbital apex syndrome, Invasive fungal sinusitis, Amphotericin B, OphthalmoplegiaAbstract
Orbital infection with fungi of the order Mucorales, termed mucormycosis or zygomycosis; is sometimes seen in immunosuppressed patients, including those with diabetic ketoacidosis and malignancy. Presentations of scopulariopsis usually mimic that of mucormycosis, diagnosis is also difficult as initial smear on potassium hydroxide mount shows a similar picture to mucormycois. We describe a case orbital infection caused by Scopulariopsis in a patient with uncontrolled diabetes who presented with acute onset of unilateral painful ophthalmoplegia, defective vision and drooping of eyelid. Surgical debridement followed by Amphotericin B and itraconazole treatment responded as well.
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Philips P, Wood WS, Rinaldi MG, Invasive hyalohyphomycosis caused by Scopulariopsis brevicaulis in a patient undergoing allogenic bone marrow transplant. Diagn Microbiol Infect Dis. 1989;12:429-32.
Swatek F, Halde C, Rinaldi MJ. Aspergillus species and other opportunistic saprophytic hyaline hyphomycetes. In: Lennette EH, Balows A, Hausler WJ, Shadomy HJ, eds. Manual of clinical microbiology. 4th ed. Washington DC: American Society for Microbiology.1985:584-94.
Sigler L, Verweij PE. Aspergillus, fusarium and other opportunistic moniliaceous fungi. In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH, eds. Manual of Clinical Microbiology. 8th ed. Washington: ASM Press,2003:1727-60.
Larone DH. Medically Important Fungi: A Guide to Identification. 3rd ed. Washington: ASM Press, 1995:195.
Neglia JP, Hurd DD, Ferrieri P, Snover DC. Invasive Scopulariopsis in the immunocompromised host. Am J Med. 1987;83:1163-6.
Morrison VA, Haake RJ, Weisdorf DJ. The spectrum of non-candida fungal infections following bone marrow transplantation. Medicine (Baltimore). 1993;72(2):78-89.
Kriesel JD, Adderson EF, Gooch WM 3rd,Pavia AT. Invasive sinonasal disease due to Scopulariopsis candida: case report and review of scopulariopsis. Clin Infect Dis. 1994;19:317-9.
Ragge NK, Hart JC, Easty DL, Tyers AG. A case of fungal keratitis caused by Sccopulariopsis brevicaulis: treatment with anti-fungal agents and penetrating keratoplasty. Br J Ophthalmol. 1990;74:561-2.
Wheat LJ, Bartlett M, Ciccarelli M, Smith JW. Opportunistic Scopulariopsis pneumonia in an immunocompromised host. South Med J. 1984;77:1608-9.
Sandoval-Denis M, Sutton DA, Fothergill AW, Cano-Lira J, Gené J, Decock CA, et al. Scopulariopsis, a Poorly Known Opportunistic Fungus: spectrum of species in clinical samples and in vitro responses to antifungal drugs. J Clin Microbiol. 2013;51:3937–43.
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