A rare presentation of amyloid goiter with renal amyloidosis in a young female

Authors

  • Tirumalasetty Sriharsha Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Raghav Raj J. Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Sudha Venkatesan Department of Pathology, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Nooka M. Reddy Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Vikrannth V. Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Vinod Raghavan Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India
  • Kannan Rajendran Department of Medicine, Saveetha Medical College, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20230706

Keywords:

Amyloid goiter, Amyloidosis, Subacute thyroiditis

Abstract

Amyloidosis is a rare systemic disorder caused by abnormal folding of normal soluble proteins leading to fibril formation in one or more body organs, systems or soft tissues. Amyloid goiter is characterized by deposits of amyloid protein in the thyroid tissue. Amyloid infiltration of thyroid gland with development of secondary goiter is rare. Here we report a case of 36-year-old female presented with progressive painless swelling over neck. Thyroid profile was normal. Ultrasound neck showed enlarged bilateral thyroid gland and isthmus. Fine needle aspiration cytology suggestive of subacute thyroiditis (granulomatous thyroiditis). Total thyroidectomy was done and biopsy sample revealed amyloid goiter.

References

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Published

2023-03-24

Issue

Section

Case Reports