Association of placental laterality with pre-eclampsia
DOI:
https://doi.org/10.18203/2349-3933.ijam20231874Keywords:
Pre-eclampsia, Lateral placenta, Central placentaAbstract
Background: The aim of this study was to observe association between placental laterality and pre-eclampsia in pregnant women.
Methods: In this retrospective study, hospital records of 300 pregnant patients who were admitted in our hospital with mild or severe pre-eclampsia between January 2019 to February 2021 were analysed.
Results: Ultrasonography performed on these pregnant women between 18 and 24 weeks revealed that 177 (59%) had a lateral placenta and 123 (41%), a central placenta, indicating that pre-eclampsia occurred more frequently in patients with a lateral placental position. Also, pre-eclampsia occurred more frequently in primigravida (first-time moms) than in multigravida (second or subsequent pregnancies), with 132 (44%) primigravida, 106 (35%) second gravida and 62 (21%) multigravidas.
Conclusions: This study revealed that the majority of pre-eclampsia patients had placentas that were positioned laterally, indicating a correlation between the two.
References
Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R. Pre-eclampsia. Lancet. 2010;376:631-44.
Villar MA, Sibai BM. Clinical significance of elevated mean arterial blood pressure in second trimester and threshold increase in systolic or diastolic blood pressure during the third trimester. Am J Obstet Gynecol.1989;160:419-23.
Conde-Agudelo A, Balizan JM, Lede R, Bergel EF. What does an elevsted mean arterial pressure in second half of pregnancy predict: gestational hypertension or preeclampsia? Am J Obstet Gynecol. 1993;169:509-14.
Fleischer A, Schulman H, Farmakides G, Bracero L, Grunfeld L, Rochelson B, et al. Uterine artery Doppler velocimetry in pregnant women with hypertension. Am J Obstet Gynecol. 1986;154(4):806-13.
Schulman H, Winter D, Farmakides G, Ducey J, Guzman E, Coury A, et al. Pregnancy surveillance with Doppler velocimetry of uterine and umbilical arteries. Am J Obstet Gynecol. 1989;160(1):192-6.
Kofinas AD, Penry M, Swain M, Hatjis CG. Effect of placental laterality on uterine artery resistance and development of preeclampsia and intrauterine growth retardation. Am J Obstet Gynecol. 1989;161(6 Pt 1):1536-9.
Pai Muralidhar V, Pillia J. Placental laterality by ultrasound- A simple yet reliable predictive test for preeclampsia. J Obstet Gynecol India. 2005;55:431-3.
Bhalerao AV, Kulkarni S. Lateral placentation by ultrasonography: A simple predictor of preeclampsia. J South Asian Feder Obst Gynae. 2013;5(2):68-71.
Jani PS, Patel UM, Gandhi MR, Thakor NC, Kakani CR. Placental laterality and uterine artery resistance as predictor of preeclampsia: a prospective study at GMERS Medical College, Dharpur-Patan, North Gujarat, India. Int J Res Med Sci. 2015;3:1484-7.
Kofinas AD, Penry M, Swain M, Hatjis CG. Effect of placental laterality on uterine artery resistance and development of preeclampsiaand intrauterine growth retardation. Am J Obstet Gynecol. 1989;161(6):153-9.
Kalanithi LEG, Illuzzi JL, Nossov VB, Frisbaek Y, Abdel-Razeq S, Copel JA, et al. Intrauterine growth restriction and placental location. J Ultrasound Med. 2007;26(11):1481-9.
Liberati M, Rotmensch S, Zannolli P, Perrino S, Celentano C, Tiboni GM. Uterine artery Doppler velocimetry in pregnant women with lateral placentas. J Perinat Med. 1997;25(2):133-8.
Magann EF, Doherty DA, Turner K, Lanneau GS, Morrison JC, Newnham JP. Second trimester placental location as a predictor of an adverse pregnancy outcome. J Perinatol. 2007;27(1):9-14.
