Infection and outcome of COVID-19 affected patients during 1st and 2nd waves in Bangladesh: a hospital based comparative study

M. Maksudul Islam Mazumder; Homayra Tahseen Hossain; Tasmina Chowdhury; Ishrat Binte Reza; Quazi Audry Arafat; H. A. M. Nazmul Ahasan

doi:10.18203/2349-3933.ijam20232204

Authors

M. Maksudul Islam Mazumder Department of Internal Medicine, Sheikh Fazilatunnessa Mujib Memorial KPJ Specialized Hospital, Gazipur, Bangladesh
Homayra Tahseen Hossain Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
Tasmina Chowdhury Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
Ishrat Binte Reza Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
Quazi Audry Arafat Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
H. A. M. Nazmul Ahasan Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2349-3933.ijam20232204

Keywords:

COVID, Clinical features, Demographic factors, 1st and 2nd wave, HRCT, Respiratory syndrome

Abstract

Background: COVID-19 emerged as one of the worst pandemics in human history in December 2019. Despite a relatively low infection rate in Bangladesh for seven weeks from mid-January, there were still 287 deaths in February, marking the lowest monthly death toll since May 2020. This study aimed to analyze the infection and outcomes of COVID-19 patients during the first and second waves in Bangladesh.

Methods: This cross-sectional observational comparative study conducted at the Popular medical college hospital, 190 COVID patients were enrolled during the first wave (Mid-June to Mid-August 2020), and 179 COVID patients were enrolled during the second wave (Mid-March to Mid-April 21).

Result: Mean age was 52.85±15.36 years in the first wave and 55.42±14.20 years in the second wave (p=0.097). Male patients predominated in both waves (p=0.082). Common symptoms, such as fever, cough, and respiratory distress, were similar. The second wave had a higher percentage of patients with diabetes. CRP levels increased in the first wave, while D-dimer levels were higher in the second wave. HRCT reports indicated minimal COVID-19 involvement. Most patients were discharged, with a small percentage referred to higher centers, and the mortality rate was not significant (p=0.600).

Conclusions: The study highlights the differences in various factors related to COVID-19 between the first and second waves of COVID-19 in Bangladesh. Although the demographic status was similar in both waves, it provides valuable insights for medical consultations.

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