Infection and outcome of COVID-19 affected patients during 1st and 2nd waves in Bangladesh: a hospital based comparative study

Authors

  • M. Maksudul Islam Mazumder Department of Internal Medicine, Sheikh Fazilatunnessa Mujib Memorial KPJ Specialized Hospital, Gazipur, Bangladesh
  • Homayra Tahseen Hossain Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
  • Tasmina Chowdhury Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
  • Ishrat Binte Reza Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
  • Quazi Audry Arafat Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh
  • H. A. M. Nazmul Ahasan Department of Medicine, Popular Medical College Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2349-3933.ijam20232204

Keywords:

COVID, Clinical features, Demographic factors, 1st and 2nd wave, HRCT, Respiratory syndrome

Abstract

Background: COVID-19 emerged as one of the worst pandemics in human history in December 2019. Despite a relatively low infection rate in Bangladesh for seven weeks from mid-January, there were still 287 deaths in February, marking the lowest monthly death toll since May 2020. This study aimed to analyze the infection and outcomes of COVID-19 patients during the first and second waves in Bangladesh.

Methods: This cross-sectional observational comparative study conducted at the Popular medical college hospital, 190 COVID patients were enrolled during the first wave (Mid-June to Mid-August 2020), and 179 COVID patients were enrolled during the second wave (Mid-March to Mid-April 21).

Result: Mean age was 52.85±15.36 years in the first wave and 55.42±14.20 years in the second wave (p=0.097). Male patients predominated in both waves (p=0.082). Common symptoms, such as fever, cough, and respiratory distress, were similar. The second wave had a higher percentage of patients with diabetes. CRP levels increased in the first wave, while D-dimer levels were higher in the second wave. HRCT reports indicated minimal COVID-19 involvement. Most patients were discharged, with a small percentage referred to higher centers, and the mortality rate was not significant (p=0.600).

Conclusions: The study highlights the differences in various factors related to COVID-19 between the first and second waves of COVID-19 in Bangladesh. Although the demographic status was similar in both waves, it provides valuable insights for medical consultations.

References

Ciotti M, Ciccozzi M, Terrinoni A, Jiang WC, Wang CB, Bernardini S. The COVID-19 pandemic. Crit Rev Clin Lab Sci. 2020;57(6):365-88.

Pokhrel S, Chhetri R. A literature review on the impact of the COVID-19 pandemic on teaching and learning. Higher Education Future. 2021;8(1):133-41.

Lone SA, Ahmad A. COVID-19 pandemic–an African perspective. Emerging Microbes Infect. 2020;9(1):1300-8.

Daniel SJ. Education and the COVID-19 pandemic. Prospects. 2020;49(1):91-6.

Pranggono B, Arabo A. COVID‐19 pandemic cybersecurity issues. Internet Technol Letters. 2021;4(2):e247.

Pradhan R, Prabheesh KP. The economics of COVID-19 pandemic: A survey. Economic analysis and policy. 2021;70:220-37.

Mehanna R, Jankovic J. Respiratory problems in neurologic movement disorders. Parkinsonism Related Disorders. 2010;16(10):628-38.

Taylor S. The psychology of pandemics. Ann Rev Clin Psychol. 2022;18:581-609.

Islam T, Talukder AK, Siddiqui N, Islam T. Tackling the COVID-19 pandemic: The Bangladesh perspective. J Publ Heal Res. 2020;9(4):2020.

Julqarnine M, Akter M, Akter T, Khoda M. The Challenges of Good Governance to Combat COVID-19. Available at: https://www.ti-bangladesh.org/beta3/images/2020/report/covid-19/Covid-Resp-Track-Full-BN-15062020.pdf. Accessed on July 7, 2023.

Age N. People leave Dhaka with a high coronavirus risk. New Age. 2020;1.

Kumar S, Nafi SM. Impact of COVID-19 pandemic on tourism: Perceptions from Bangladesh. 2020;22.

Al Mamun F, Hosen I, Misti JM, Kaggwa MM, Mamun MA. Mental disorders of Bangladeshi students during the COVID-19 pandemic: a systematic review. Psychol Res Behavior Management. 2021:645-54.

Hossain MI, Parvin S, Islam MS, Alam MJ, Podder S, Datta R et al. Demographic profile and outcome of patients admitted to a COVID dedicated hospital in Bangladesh during the second wave. Medicine. 2021;100(37).

Budhiraja S, Indrayan A, Aggarwal M, Jha V, Jain D, Tarai B et al. Differentials in the characteristics of COVID-19 cases in Wave-1 and Wave-2 admitted to a network of hospitals in North India. Medrxiv. 2021:2021-06.

Ghoshal UC, Ghoshal U, Rahman MM, Mathur A, Rai S, Akhter M, et al. Post‐infection functional gastrointestinal disorders following coronavirus disease‐19: A case–control study. J Gastroenterol Hepatol. 2022;37(3):489-98.

Iftimie S, López-Azcona AF, Vallverdú I, Hernández-Flix S, De Febrer G, Parra S et al. First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain. PloS One. 2021;16(3):e0248029.

Mowla SG, Azad KA, Kabir A, Biswas S, Islam MR, Banik GC et al. Clinical profile of 100 confirmed COVID-19 patients admitted to Dhaka medical college Hospital, Dhaka, Bangladesh. J Bangl College Physicians Surgeons. 2020:29-36.

Nelson LM, Simard JF, Oluyomi A, Nava V, Rosas LG, Bondy M et al. US public concerns about the COVID-19 pandemic from the results of a survey given via social media. JAMA Internal Med. 2020;180(7):1020-2.

Singh AK, Gupta R, Misra A. Comorbidities in COVID-19: Outcomes in the hypertensive cohort and controversies with renin-angiotensin system blockers. Diabetes Metabolic Syndrome Clin Res Rev. 2020;14(4):283-7.

Alam SZ, Al Muid SM, Akhter A, Rahman AS, Al Emran M, Al Mostakim MT. HRCT chest evaluation of COVID-19 patients: experience in Combined Military Hospital Dhaka, Bangladesh. J Bangladesh College Physicians Surgeons. 2020:21-8.

Oliveira E, Parikh A, Lopez-Ruiz A, Carrilo M, Goldberg J, Cearras M et a. ICU outcomes and survival in patients with severe COVID-19 in the largest health care system in central Florida. PloS One. 2021;16(3):e0249038.

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Published

2023-07-26

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Section

Original Research Articles