A study to establish the relation of antibiotics and steroids in fungal growth occurring in CSOM patients

Rachna Dhingra, Shamim Monga, Gurpreet Kaur, Manpreet Kaur, Manpreet ., Varun Aggarwal, Gurpal Singh


Background: Otitis media is known to be one of most common childhood infections and a leading reason for antibiotic prescriptions in the developed world. Fungal infections superimposed over chronic suppurative. Otitis media is suspected when the discharging ear does not respond to local antibiotic ear drops. The aim of the study is to analyze the relation of antibiotics and steroids in fungal growth occurring in CSOM patients.

Methods: Total 150 cases were selected from OPD of ENT department, Government Medical College, Rajindra Hospital, Patiala and divided under two groups: Control group and study group.

Results: The antibiotic drop apart from moist and alkaline medium of discharge appears to be mainly responsible for fungal growth and when steroids are added the fungal growth incidence is increased. Thus local drops should be used with great care in treating chronic suppurative otitis media.

Conclusions: Local drops with some anti-fungal agents may be the ideal treatment in chronic suppurative otitis media.


CSOM, Antibiotic, Otitis

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Healy GB. Otitis media and middle ear effusions. In. Ballenger JJ. The Ear, Williams and Williams. Baltimore. 1996;1003-9.

Bluestone CB, Klein JO. Epidemiology, Otitis media in infants and children. WB Saunders, Philadelphia; 2001:58-78.

Sen Gupta RP, Kacker SK. Otomycosis. Indian J Med Sci. 1978;32(1-2):5-7.

Fauci AS, Dale DC. The effect of in vivo hydrocortisone on subpopulations of human lymphocytes. J Clin Invest. 1974;53(1):240-6.

Baruah PC, Aggarwal SC, Arora MML, Mehra YN. Clinical and microbiological studies in suppurative otitis media in Chandigarh. Indian Journal of otolaryngology. 1972;24(4):157-60.

Pasternale NI, Brysin VG, Danilova RD. Sensitization to mould and yeast-like fungi in chronic purulent otitis media. Vestnik Otorinolaringologii.1973;35(2):35-8.

Talwar P, Chakraborty A, Kaur P, Pahwa RK, Mittal A, Mehra YN Fungal infections of ear with special reference to chronic suppurative otitis media. Mycopathologia. 1988;104(1):47-50.

Mittal A, Mann SBS, Panda NK, Mehra YN, Talwar P. Secondary fungal infections in chronic suppurative otitis media. Indian J Otolaryngol Head Neck Surg. 1997;49(2):112-6.

Nwankwo EO, Salisu AD. Bacteriology of chronic discharging ears of patients in Kano, Nigeria. Journal of Medical Laboratory Sciences. 2005;14(1):57-62.

Mirza IA, Ali L, Mahmood A. Microbiology of chronic suppurative otitis media – Experience at Bahawalpur. Pakisthan armed forces medical journal. 2008;58(4):372-6.

Khanna V, Chander J, Nagarkar NM, Dass A. Clinicomicrobiologic evaluation of active tubotympanic type chronic suppurative otitis media Otolaryngol. 2000;29(3):148-53.

Kunel’skaia VIa. Fungal lesions of postoperative ear cavities. Vestn Otorinolaringol. 1967;29(1):55-9.