Prevalence of coronary artery disease and the associated risk factors among the patients attending the medicine department in a tertiary care teaching hospital in the North Eastern Zone in India

Authors

  • Naushad Akhtar Department of Medicine, MGM Medical College, Kishanganj, Bihar, India
  • Pritama Paul Department of Pharmacology, MGM Medical College, Kishanganj, Bihar, India
  • Tapas Kumar Department of Medicine, MGM Medical College, Kishanganj, Bihar, India
  • Uttam K. Paul Department of Medicine, MGM Medical College, Kishanganj, Bihar, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20233565

Keywords:

Coronary artery disease, Risk factors, Prevalence, Urban, Rural

Abstract

Background: Coronary artery disease (CAD) is characterized by the narrowing or obstruction of coronary arteries, leading to inadequate blood supply to the heart. In India, CAD has become a major public health issue, particularly in the North Eastern Zone. This study aims to illuminate CAD, its causes, and its unique prevalence patterns within India, with a specific focus on the North Eastern Zone.

Methods: A cross-sectional study was conducted over a year at a tertiary care teaching hospital in India's North Eastern Zone. A sample of 154 patients with coronary artery disease was selected through structured questionnaires, clinical examinations, vital signs assessments, and 12-lead ECGs. Data analysis was done with proper equipment.

Results: The study revealed an overall CAD prevalence of 4.24% among 2468 patients attending the Medicine OPD. Males had a higher prevalence across age groups, except for the 20-30-year-olds, where no females participated. Urban areas exhibited a significantly higher CAD prevalence (68.83%) compared to rural areas (31.17%). Statistically significant gender differences were observed in several risk factors, with males more likely to exhibit hypertension, hyperlipidemia, diabetes mellitus, obesity, smoking, and ischemic heart disease. Urban residents also showed a higher prevalence of various CAD risk factors compared to rural residents, except for alcohol consumption, which was more common in rural areas.

Conclusions: The findings corroborate existing literature, highlighting gender disparities and urban-rural differences in CAD prevalence and risk factors. This study contributes valuable insights into CAD epidemiology in India, particularly in the North Eastern Zone.

References

Keates AK, Mocumbi AO, Ntsekhe M, Sliwa K, Stewart S. Cardiovascular disease in Africa: epidemiological profile and challenges. Nat Rev Cardiol. 2017;14(5):273-93.

Centers for Disease Control and Prevention. Coronary artery disease. 2022. Available at: https://www.cdc.gov/heartdisease/coronary_ad.htm. Accessed on 19 September 2023.

Shahjehan RD, Bhutta BS. Coronary Artery Disease. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2023.

Hajar R. Risk factors for coronary artery disease: Historical perspectives. Heart Views. 2017;18(3):109.

Brown JC, Gerhardt TE, Kwon E. Risk factors for coronary artery disease. StatPearls Publishing. 2023.

Prabhakaran D, Jeemon P, Roy A. Cardiovascular diseases in India: Current epidemiology and future directions. Circulation. 2016;133(16):1605-20.

Sreeniwas Kumar A, Sinha N. Cardiovascular disease in India: A 360 degree overview. Med J Armed Forces India. 2020;76(1):1-3.

Huffman MD, Prabhakaran D, Osmond C, Fall CHD, Tandon N, Lakshmy R, et al. Incidence of cardiovascular risk factors in an Indian urban cohort. J Am Coll Cardiol. 2011;57(17):1765-74.

Zachariah G, Harikrishnan S, Krishnan MN, Mohanan PP, Sanjay G, Venugopal K, et al. Prevalence of coronary artery disease and coronary risk factors in Kerala, South India: A population survey – Design and methods. Indian Heart J. 2013;65(3):243-9.

Mohan V, Venkatraman JV, Pradeepa R. Epidemiology of cardiovascular disease in type 2 diabetes: The Indian scenario. J Diabetes Sci Technol. 2010;4(1):158-70.

Sanchis-Gomar F, Perez-Quilis C, Leischik R, Lucia A. Epidemiology of coronary heart disease and acute coronary syndrome. Ann Transl Med. 2016;4(13):256.

Ajay VS, Prabhakaran D. Coronary heart disease in Indians: Implications of the INTERHEART study. Indian J Med Res. 2010;132(5):561.

Krishnan MN, Zachariah G, Venugopal K, Mohanan PP, Harikrishnan S, Sanjay G, et al. Prevalence of coronary artery disease and its risk factors in Kerala, South India: a community-based cross-sectional study. BMC Cardiovasc Disord. 2016;16(1).

Cheong SS, Chin KY, Ugusman A, Aminuddin A. Cardiovascular profiles of younger and older coronary artery disease patients in Asian and western regions. Curr Epidemiol Rep. 2023;10(2):85-114.

Crimmins EM, Shim H, Zhang YS, Kim JK. Differences between men and women in mortality and the health dimensions of the morbidity process. Clin Chem. 2019;65(1):135-45.

Goyal A, Kahlon P, Jain D, Soni RK, Gulati R, Chhabra ST, et al. Trend in prevalence of coronary artery disease and risk factors over two decades in rural Punjab. Heart Asia. 2017;9(2):e010938.

Kumar R, Singh MC, Singh MC, Ahlawat SK, Thakur JS, Srivastava A, et al. Urbanization and coronary heart disease: a study of urban-rural differences in northern India. Indian Heart J. 2006;58(2).

Centers for Disease Control and Prevention. Women and heart disease. 2023. Available at: https://www.cdc.gov/heartdisease/women.htm. Accessed on 19 September 2023.

Ardeshna DR, Bob-Manuel T, Nanda A, Sharma A, Skelton WP IV, Skelton M, et al. Asian-Indians: a review of coronary artery disease in this understudied cohort in the United States. Ann Transl Med. 2018;6(1):12.

Gong W, Wei X, Liang Y, Zou G, Hu R, Deng S, et al. Urban and rural differences of acute cardiovascular disease events: A study from the population-based real-time surveillance system in Zhejiang, China in 2012. PLoS One. 2016;11(11):e0165647.

Downloads

Published

2023-11-24

Issue

Section

Original Research Articles