Orbital pseudolymphoma: a benign condition mimicking malignancy


  • Nirupama Kasturi Department of Ophthalmology, JIPMER, Puducherry, India
  • Salwa Kaidakath Department of Ophthalmology, JIPMER, Puducherry, India
  • Mary Stephen Department of Ophthalmology, JIPMER, Puducherry, India
  • Jayasri P. Department of Ophthalmology, JIPMER, Puducherry, India




Orbital pseudolymphoma, Proptosis, Compressive optic neuropathy, Disc edema, Steroids


Orbital lymphomas are not a rare condition that causes systemic and ocular morbidity, in which vision loss often occurs due to compressive optic neuropathy, and whose treatment is complex, involving chemotherapy and radiotherapy. We report a 54-year-old male with protrusion of the right eye associated with mild diminution of vision for one year, limitation of extraocular movements, and a relative afferent pupillary defect with optic disc edema. Imaging revealed a well-defined soft tissue lesion filling the retro-orbital intraconal space, suggestive of orbital lymphoma. Incisional biopsy and fine needle aspiration cytology revealed the lesion to be a reactive lymphoid hyperplasia. Following the administration of oral steroids, the patient showed significant improvement. To our knowledge, a benign lesion with an aggressive presentation is rare, and histopathology plays an important role in diagnosis and management.


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