Perinatal outcome in pregnancy induced hypertension cases at GMERS Medical College, Dharpur-Patan, North Gujarat region, India: a prospective study


  • Mayur R. Gandhi Department of Obstetrics and Gynecology, GMERS Medical College, Dharpur-Patan-384265, Gujarat, India
  • Parul S. Jani Department of Obstetrics and Gynecology, GMERS Medical College, Dharpur-Patan-384265, Gujarat, India
  • Uday M. Patel Department of Obstetrics and Gynecology, GMERS Medical College, Dharpur-Patan-384265, Gujarat, India
  • C. R. Kakani Department of Obstetrics and Gynecology, GMERS Medical College, Dharpur-Patan-384265, Gujarat, India
  • Nilesh C. Thakor Department of Community Medicine, GMERS Medical College, Dharpur-Patan-384265, Gujarat, India
  • Nidhi Gupta District Child Survival Officer, UNICEF, Dahod, Gujarat, India


PIH, Preeclampsia, Eclamsia, Perinatal mortality, LBW


Background: Pregnancy Induced Hypertension (PIH) is one of the common conditions of unknown etiology which increases risk of maternal and perinatal morbidity and mortality. Objectives: To study the maternal and perinatal outcome in pregnancy induced hypertension.

Methods: A prospective study was carried out from February 2014 to January 2015 in the Department of obstetrics and gynecology of GMERS medical college and hospital, Dharpur-Patan, North Gujarat, India. A total of 95 pregnant women with PIH were enrolled in the study. A pre-tested interview tool was used to collect necessary information such as detailed history, clinical examination findings and investigations performed. Results were analyzed using SPSS 17.0 (Trial Version).

Results: In the present study, the overall incidence of PIH was 12.8%, which includes preeclampsia in 11.4% and eclampsia in 1.4%. Out of total 95 cases, 69 (72.6%) were emergency cases. 72 (75.7%) cases were from rural area. The most common symptoms were labour pains (48.4%) followed by eclampsia (11.5%). 51 (53.7%) women delivered normally. Eclampsia was the commonest maternal complication affecting 11.6% of cases. Out of total 95 births, perinatal deaths were occurred in 22 (23.15%) cases. Out of 22 perinatal deaths, 13 (61.2%) were still births and 9 (42.8%) were neonatal deaths.

Conclusions: Pregnancy induced hypertension is a common medical disorder seen associated with pregnancy especially among young primigravidas, who remain unregistered during pregnancy. Maternal and fetal morbidity and mortality can be reduced by early recognition and institutional management. 


Chen XK, Wen SW, Smith G, Yang Q, Walker M. Pregnancy-induced hypertension is associated with lower infant mortality in preterm singletons. BJOG. 2006;113(5):544-51.

Brown MA, Hague WM, Higgins J, Lowe S, McCowan L, Oats J, et al. Australasian Society of the Study of Hypertension in Pregnancy. The detection, investigation and management of hypertension in pregnancy: full consensus statement. Aust N Z J Obstet Gynaecol. 2000;40(2):139-55.

Barrilleaux PS, Martin JN. Hypertensive therapy during pregnancy. Clin Obstet Gynecol. 2002;45(1):22-34.

Dutta DC. Hypertensive disorders in pregnancy. In: Dutta DC, eds. Text book of Obstetrics Including Perinatology and Contraception. 6th ed. Calcutta: New Central Book Agency; 2004: 221-242.

Bhattacharya Sudhindra Mohan. Pregnancy induced hypertension and prior trophoblastic exposure. J Obstet Gynecol India. 2004;54(6):568-70.

Shalini K, Ruchi Sehgal. Management of obstetric hypertensive crisis. Obstet Gynaecol Today. 2007;12:450-2.

Sudarsan Saha, Samir Ghosh Roy, R. P. Ganguly, A. Das. Comparative study on the efficacy of magnesium sulphate and diazepam in the management of eclampsia in a peripheral rural medical college (A cross over study of 440 cases). J Obstet Gynecol India. 2002;52(3):69-72.

Tukur J, Umar BA, Rabi’u A. Pattern of eclampsia in a tertiary health facility situated in a semi-rural town in Northern Nigeria. Ann Afr Med. 2007 Dec;6(4):164-7.

Villar J, Carroli G, Wojdyla D, Abalos E, Giordano D, Ba'aqeel H, et al. Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions? Am J Obstet Gynecol. 2006;194:921-31.

Duckitt K, Harrington D. Risk factors for preeclampsia at antenatal booking: systematic review of controlled studies. BMJ. 2005;330:565-77.

Audrey F. Sastlas, David R. Olson, Adele L. Franks, Hani K. Atrash, Robert Pokras. Epedimiology of preeclampsia and eclampsia in the United States, 1979-1986. Am J Obstet Gynecol. 1990;163:460-5.

Jiménez R, Cazenave H, Perucca E, Pavez A, Loyola E. Eclampsia at the Rancagua regional hospital. Rev Chil Obstet Ginecol. 1992;57(2):67-71.

Oladokun A, Okewole AI, Adewole IF, Babarinsa IA. Evaluation of cases of eclampsia in the University college hospital, Ibadan over a 10 year period. West Afr J Med. 2000;19(3):192-4.

Miguil M, Chekairi A. Eclampsia, Study of 342 cases. Hypertens Pregnancy. 2008;27(2):103-11.

Dissanayake VH, Samarasinghe HD, Morgan L, Jayasekara RW, Seneviratne HR, Pipkin FB. Morbidity and mortality associated with preeclampsia at two tertiary care hospitals in Sri Lanka. J Obstet Gynaecol Res. 2007;33(1):56-62.

Al-Mulhim AA, Abu-Heija A, Al-Jamma F, El-Harith el-HA. Preeclampsia: maternal risk factors and perinatal outcome. Fetal Diagn Ther. 2003;18(4):275-80.

Farid Mattar, Baha M. Sibai. Risk factors for maternal morbidity. Am J Obstet Gynecol. 2000;182:307-12.

Igberase GO, Ebeigbe PN. Eclampsia: ten-years of experience in a rural tertiary hospital in the Niger delta, Nigeria. J Obstet Gynaecol. 2006;26(5):414-7.

Shaheen B, Hassan L, Obaid M. Eclampsia, a major cause of maternal and perinatal mortality: a prospective analysis at a tertiary care hospital of Peshawar. J Pak Med Assoc. 2003;53(8):346-50.

Kapoor M, Agrawal N, Jain PK, Sethi RS, Gupta U, Goyal Latika. Perinatal outcome in hypertensive disorders in pregnancy. J Obstet Gynecol India. 1991;41:162-5.






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