A study on fibro-calculous pancreatic diabetes conducted in a tertiary medical institution in Northern Bihar

Authors

  • Animesh Paul Department of General Medicine, MGM Medical College, Kishanganj, Bihar, India
  • Yuvraj Singh Rathore Department of General Medicine, MGM Medical College, Kishanganj, Bihar, India
  • Naushad Akhtar Department of General Medicine, MGM Medical College, Kishanganj, Bihar, India
  • Uttam Kumar Paul Department of General Medicine, MGM Medical College, Kishanganj, Bihar, India

DOI:

https://doi.org/10.18203/2349-3933.ijam20241019

Keywords:

Fibro-calculous, Diabetes, Pancreatic, Secondary

Abstract

Fibro-calculous pancreatic diabetes (FCPD), which is seen in tropical areas and is caused by idiopathic nonalcoholic chronic pancreatitis, is characterized by pancreatic calcification and stomach pain. One female patient and nine male patients were identified as having FCPD. Half of the patients were under 30 years old, with an average age of 28.44±7.07. Seven individuals had diabetes for a shorter period of time than five years. Four patients reported with problems related to various infections, while six patients had osmotic complaints due to uncontrolled diabetes. With a mean waist-hip ratio of 0.89 and a mean BMI of 19.42, all of the patients were thinly built. With mean FBS of 231 mg/dl, PPBS of 469 mg/dl, and HbA1c of 11.96, all patients had uncontrolled diabetes. Microvascular issues affected 30% of the patients, while none of the patients experienced macrovascular complications. A rare type of secondary diabetes called FCPD is becoming more widespread in northern states like Bihar. 

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References

Mohan V, Premalatha G, Pitchumoni CS. Tropical chronic pancreatitis: an update. J Clin Gastroenterol. 2003;36(4):337-46.

Zuidema PJ. Cirrhosis and disseminated calcification of the pancreas in patients with malnutrition. Trop Geographical Med. 1959;11(1):70-4.

Mohan V, Farooq S, Deepa M. Prevalence of fibrocalculous pancreatic diabetes in Chennai in southern India. J Pancreas. 2008;9(4):489-92.

Pitchumoni CS. Special problems of tropical pancreatitis. Clin Gastroenterol. 1984;13(3):941-59.

McMillan DE, Geevarghese PJ. Dietary cyanide and tropical malnutrition diabetes. Diabetes Care. 1979;2(2):202-8.

Braganza JM. The pancreas. In: Pounder RG (ed) Recent advances in gastroenterology. Churchill Livingstone, London. 1988;251-80.

Braganza JM, Schofield D, Snehalatha C, Mohan V. Micronutrient antioxidant status in tropical compared with temperate-zone chronic pancreatitis. Scand J Gastroenterol. 1993;28(12):1098-104.

Tandhanand-Banchuin N, Kespichayawatana W, Vannasaeng S, Sarasombath S. Presence of autoimmunity to pancreatic antigens in a patient with fibrocalculous pancreatic diabetes. Diabetes Res Clin. 1992;18(1):17-21.

Fida S, Myers M, Mackay IR, Zimmet PZ, Mohan V, Deepa R, et al. Antibodies to diabetes-associated autoantigens in Indian patients with Type 1 diabetes: prevalence of anti-ICA512/IA2 and anti-SOX13. Diabetes Res Clin Pract. 2001;52(3):205-11.

Sanjeevi CB, Kanungo A, Shtauvere A, Samal KC, Tripathi BB. Association of HLA class II alleles with different subgroups of diabetes mellitus in Eastern India identify different associations with IDDM and malnutrition-related diabetes. Tissue Antigens. 1999;54(1):83-7.

Chowdhury ZM, McDermott MF, Davey S, Hassan Z, Sinnott PJ, Hemmatpour SK, et al. Genetic susceptibility to fibrocalculous pancreatic diabetes in Bangladeshi subjects: a family study. Genes Immun. 2002;3(1):5-8.

Mohan V, Premalatha G. Fibrocalculous pancreatic diabetes. Int J Diabetes. 1995;3:71-82.

Yajnik CS, Shelgikar KM. Fibrocalculous pancreatic diabetes in Pune, India. Clinical features and follow-up for 7 yr. Diabetes Care. 1993;16(6):916-21.

Levitt NS, Adams G, Salmon J, Marks IN, Musson G, Swanepoel C, et al. The prevalence and severity of microvascular complications in pancreatic diabetes and IDDM. Diabetes Care. 1995;18(7):971-4.

Rema M, Rajendran B, Ramachandran A, Viswanathan M, Kohner EM. Retinopathy in tropical pancreatic diabetes. Arch Ophthalmol. 1985;103(10):1487-9

Kanta Barman K, Padmanabhan M, Premalatha G, Deepa R, Rema M, Mohan V. Prevalence of diabetic complications in fibrocalculous pancreatic diabetic patients and type 2 diabetic patients: a cross-sectional comparative study. J Diabetes Complications. 2004;18(10):264-70.

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Published

2024-04-26

How to Cite

Paul, A., Rathore, Y. S., Akhtar, N., & Paul, U. K. (2024). A study on fibro-calculous pancreatic diabetes conducted in a tertiary medical institution in Northern Bihar. International Journal of Advances in Medicine, 11(3), 243–245. https://doi.org/10.18203/2349-3933.ijam20241019

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