The relationship between knowledge and willingness COVID-19 vaccination among adolescence, in Samarinda, Indonesia


  • Sitti M. Arif Department of Dermato-Venereology, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Indonesia
  • Dian A. Fitriani Department of Public Health, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Indonesia
  • Sagena N. Carisma Bachelor of Medicine Program, Medicine Study Program, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Indonesia



Knowledge, Vaccination, COVID-19, Adolescence


Background: In 2020, infections caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are still a pandemic, including in Indonesia. Numerous efforts have been made to reduce morbidity and mortality rates caused by the virus, including vaccination. The existence of a vaccine for COVID-19 in the Indonesian community faces pros and cons. The achievement rate of vaccination, in general, is still not as expected. To accelerate vaccination, the government through the Ministry of Health has issued a circular on the acceleration of COVID-19 vaccination for children from 12-17 years old. The study aims to assess the relationship between the level of knowledge and willingness to vaccinate against COVID-19 in adolescents from 12-17 years old in Sambutan Village, Samarinda city, Indonesia.

Methods: This study is observational analytic with a cross-sectional design. We took samples through online questionnaires distributed to adolescents aged 12-17 years old, in Sambutan village, Samarinda city from September to December 2021.

Results: The sample was 179 people, consisting of 86 people (48.04%) male and 93 people (51.96%) female. Based on the knowledge level, 144 (80.4%) have good knowledge and 35 (19.6%) have less knowledge about vaccination. As for the willingness to vaccinate, 150 (83.8%) people are willing, and 29 (16.2%) are unwilling to be vaccinated. The analysis test, obtained p<0.001, indicating that there is a relationship between the level of knowledge and willingness to vaccinate.

Conclusions: The better adolescents comprehend vaccination, then their willingness to be vaccinated is higher.


Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID- 19) outbreak. J Autoimmun. 2020;109:102433.

Afifi TO, Salmon S, Taillieu T, Stewart-Tufescu A, Fortier J, Driedger SM. Older adolescents and young adults willingness to receive the COVID-19 vaccine: Implications for informing public health strategies. Vaccine. 2021;39(26):3473-9.

Wu YC, Chen CS, Chan YJ. The outbreak of COVID-19: An overview. J Chin Med Assoc. 2020;83(3):217-20.

Saadat S, Rawtani D, Hussain CM. Environmental perspective of COVID-19. Sci Total Environ. 2020;728:138870.

Velavan TP, Meyer CG. The COVID‐19 epidemic. Trop Med Int Health. 2020;25(3):278-80.

Ciotti M, Angeletti S, Minieri M, Giovannetti M, Benvenuto D, Pascarella S, et al. COVID-19 Outbreak: An Overview. Chemotherapy. 2019;64(5-6):215-23.

Rangayasami A, Kannan K, Murugesan S, Radhika D, Sadasivuni KK, Reddy KR, et al. Influence of nanotechnology to combat against COVID-19 for global health emergency: A review. Sens Int. 2021;2:100079.

Maude RR, Jongdeepaisal M, Skuntaniyom S, Muntajit T, Blacksell SD, Khuenpetch W, et al. Improving knowledge, attitudes and practice to prevent COVID-19 transmission in healthcare workers and the public in Thailand. BMC Public Health. 2021;21(1):749.

Jeyanathan M, Afkhami S, Smaill F, Miller MS, Lichty BD, Xing Z. Immunological considerations for COVID-19 vaccine strategies. Nat Rev Immunol. 2020;20(10):615-32.

Graham BS. Rapid COVID-19 vaccine development. Science. 2020;368(6494):945-6.

Rzymski P, Borkowski L, Drąg M, Flisiak R, Jemielity J, Krajewski J, et al. The Strategies to Support the COVID-19 Vaccination with Evidence-Based Communication and Tackling Misinformation. Vaccines. 2021;9(2):109.

Sa’diyah M, Masuwd MA, Supandi AchF. Legal Problems Using AstraZeneca Vaccine: Hermeneutic Analysis of the Fatwa of the Indonesian Ulema Council. JIL J Islam Law. 2022;3(1):1-16.

He Q, Mao Q, Zhang J, Bian L, Gao F, Wang J, et al. COVID-19 Vaccines: Current Understanding on Immunogenicity, Safety, and Further Considerations. Front Immunol. 2021;12:669339.

Zaid Z, Al Bahy MP. Examining Factors Influencing Halal Covid-19 Vaccination Intention Among The Muslim Communities. Psikis J Psikol Islami. 2022;8(1):40-53.

Mardian Y, Shaw-Shaliba K, Karyana M, Lau CY. Sharia (Islamic Law) Perspectives of COVID-19 Vaccines. Front Trop Dis. 2021;2:788188.

Sun S, Lin D, Operario D. Interest in COVID-19 vaccine trials participation among young adults in China: Willingness, reasons for hesitancy, and demographic and psychosocial determinants. Prev Med Rep. 2021;22:101350.

Khatatbeh M, Albalas S, Khatatbeh H, Momani W, Melhem O, Al Omari O, et al. Children’s rates of COVID-19 vaccination as reported by parents, vaccine hesitancy, and determinants of COVID-19 vaccine uptake among children: a multi-country study from the Eastern Mediterranean Region. BMC Public Health. 2022;22(1):1375.

Octavius GS, Yanto TA, Heriyanto RS, Nisa H, Ienawi C, Pasai HE. COVID-19 vaccination acceptance in Jambi City, Indonesia: A single vaccination center study. Vacunas. 2022;23:S8-17.

Firdaus SU. The urgency of legal regulations existence in case of COVID-19 vaccination refusal in Indonesia. J Forensic Leg Med. 2022;91:102401.

Susilawaty A, Noviyanto F, Afrianty I, Syahputra A, Kurniasari L, Handoko L, et al. Attitude, Risk Perception and Public Acceptance against Coronavirus Disease 2019 Vaccination in Indonesia. Open Access Maced J Med Sci. 2021;9(E):717-21.

Data from General Directorate of Prevention and Control Disease, the Ministry of Health, Indonesia. 2021. Available at: default/files/document-library/document/INDONE SIA%20NAPHS.PDF. Accessed on 17 November 2023.

Mohamed NA, Solehan HM, Mohd Rani MD, Ithnin M, Che Isahak CI. Knowledge, acceptance and perception on COVID-19 vaccine among Malaysians: A web-based survey. PLoS One. 2021;16(8):e0256110.

Bunchuay T. Willingness of Thai adolescent to get vaccinated against coronavirus disease 2019: a cross-sectional study in Bangkok, Thailand. Int J Med Sci Public Health. 2021;10(2):232-8.

Euser S, Kroese FM, Derks M, de Bruin M. Understanding COVID-19 vaccination willingness among youth: A survey study in the Netherlands. Vaccine. 2022;40(6):833-6.

Wirunpan M. Knowledge, attitudes, and willingness of adolescents towards coronavirus disease 2019 vaccine in Bangkok, Thailand. Int J Med Sci Public Health. 2021;10(2):1.

Fazel M, Puntis S, White SR, Townsend A, Mansfield KL, Viner R, et al. Willingness of children and adolescents to have a COVID-19 vaccination: Results of a large whole schools survey in England. EClinicalMedicine. 2021;40:101144.






Original Research Articles