Prevalence of melanoma and nonmelanoma malignancies in patients visiting dermatology clinics in Ardabil City, 2002-2013


  • Alireza Mohebbipour Department of Dermatology, Ardabil Branch, Islamic Azad University,Ardabil, Iran
  • Firouz Amani Department of Biostatistics, Faculty of Medicine, Ardabil University of Medical Science, Ardabil, Iran


Skin cancer, Incidence rate, Iran, Melanoma


Background: BCC and SCC are the most prevalent malignant non-melanoma skin tumors. BCC is the most common skin tumor in white-skinned people, and as one ages, after being 40 year-old, incidence rate of BCC increases. SCC has the next rank and is more common in middle-aged and old persons. The present study addresses the prevalence of melanoma and non-melanoma malignancies in patients visiting dermatology clinics in Ardabil during 2002-2013.

Methods: This study was of retrospective descriptive type. Approximately out of 100000 medical records of patients visiting dermatology clinics, 371 cases were chosen. The selected cases had undergone biopsy on suspicion of malignancy and their pathological response was attached to the record. Data were analyzed through SPSS, version 19, and descriptive as well as inferential statistical tests were used.

Results: The prevalence of malignant skin tumors was 0.37%. 48% of cases were male, and 52% were females. The mean age of patients was 62.4 with a standard deviation of 15, and individuals of 50-70 age range had the peak incidence (46.1%). BCC was the most prevalent lesion (72%). Nose was the most common area for skin tumors (35.6%). For BCC the mean age was 62 ± 14, and for SCC it was 64.6 ± 17.  

Conclusions: According to the results, BCC was the most prevalent tumor. Skin tumors were mostly observed among females, and the most common locus was nose.


WHO. The top 10 causes of death in 2012, 2012. Available at:

Omar S, Alieldin NH, Knatib OM. Cancer magnitude, challenges and control in the Eastern Mediterranean region. East Mediterr Health. 2007;13(6):1486.

Marjani A, Kabir MJ. Male skin cancer incidence in Golestan province, Iran. J Pak Med Assoc. 2009;59(5):287-9.

Shariatzadeh SMA, Hamta A, Soleimani Mehranjani M, Rasooli Z. Determination of chromosomal changes in DMBA-induced skin cancer in SD rat strains. J Arak Univ Med Sci. 2009;12(2):73-87.

Mahmoodabad SS, Noorbala MT, Mohammadi M, Rahaei Z, Ehrampush MH. Knowledge, attitude, and performance of students toward skin cancer in Yazd, 2009. Int J Dermatol. 2011;50(10):1262-5.

Yazdanfar A, Ghasemi E. Frequency of skin cancers in Hamedan from 1991 to 2007. Dermatol Cosm. 2011;2:115-23.

WHO. Skin cancers. What are the different types of skin cancer? 2012. Available at: Accessed 12 July 2012.

Lucas R, McMichael T, Smith W, Armstrong B. Solar ultraviolet radiation. Global burden of disease from solar ultraviolet radiation. Environ Burden Dis Series. 2006;13:1-17.

Thomas PH. Skin malignancy. In: Thomas PH, eds. Clinical Dermatology. 4th ed. USA: Mosby; 2007: 724-795.

Irvin M. Freedberg, Arthur Z. Elsen, Klays Wolff, K. Frank Austen, Lowwell A. Gold Smith, Stephen I. Kath, et al. Squamous cell carcinoma. In: Irvin M. Freedberg, Arthur Z. Elsen, Klays Wolff, K. Frank Austen, Lowwell A. Gold Smith, Stephen I. Kath, et al., eds. Fitzpatrick’s Dermatology in Medicine. 5th ed. New York, NY: McGraw-Hill; 1999: 840-863.

Farahmand M, Almasi-Hashiani A, Hassanzade J, Moghadami M. Childhood cancer Epidemiology based on cancer registry’s data of Fars province of Iran. Koomesh. 2011;13:8-13.

Nabizadeh R, Salehi Shahidi SH, Younesian M, Naddafi K. Evaluation of the relationship Between global ultraviolet index in different regions of Iran and skin cancer in 1383. Iran J Health Environ. 2010;2:258-67.

Afzali M, Mirzaei M, Saadati H, Mazloomi-Mahmood-Abadi S. Epidemiology of skin cancer and changes in its trends in Iran. KAUMS J (FEYZ). 2013;17(5):501-11.

Leiter U1, Garbe C. Epidemiology of melanoma and nonmelanoma skin cancer--the role of sunlight. Adv Exp Med Biol. 2008;624:89-103.

Mackie RM, Quinin AG. Non-melanoma skin cancer and other epidermal skin tumors. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Rook’s Textbook of Dermatology. 7th ed. Oxford: Blackwell Science Publication; 2004: 36.1-36.50.

Diepgen TL, Mahler V. The epidemiology of skin cancer. Br J Dermatol. 2002;146:1-6.

Mobarakabadi A, Rajabi R, Khani Y, Almasi A. Epidemiology of skin cancer in Markazi Province, Iran. Dermatol Cosm. 2013;4:120-6.

Zamanian A, Pilehvar M, Monsef AR. Anatomical location of basal cell carcinoma in relation to histopathological subtypes: analysis of 189 cases in Hamadan Sina hospital during 1997-99. Iran J Dermatol. 2004;7(27):140-4.

Pirzadeh A, Setoudeh M, Ghader B. Study prevalence of skin tumors in patients hospitalized in Fatemi Hospital in last five years. (un published paper).

William FA, William CH, Charles RK. Changes in non-melanoma skin cancer incidence between 1977-1999 in North Central New Mexico. Cancer Epidemiol Biomark Prev. 2003;12:1105-8.

Stang A, Stegmaier C, Jockel K. Non melanoma skin cancer in the Federal state of Saarland, Germany, 1995-1999. Br J Cancer. 2003;89:1205-8.

Amouzgar MH, Yazdanpanah MJ, Ebrahimirad M. Frequency of different skin cancer in Qaem hospital of Mashhad, from 1975-1995: a cross-sectional study. Iran J Dermatol. 2006;19:28-34.

Wallberg P, Skog E. The increasing incidence of basal cell carcinoma. Br J Dermatol. 1994;131:914-5.

Grossman D, Leffell D. Squamous cell carcinoma. In: Wolff K, Goldsmith S, Katz S Gilchrest B, Paller A, Leffell D, eds. Fitzpatrick’s Dermatology in General Medicine. 7th ed. New York: McGraw-Hill; 2008: 1028-1036.

Rahnama Z, Haghdoost AA. Relationship of sex, age and site of the skin squamous cell carcinoma with pathological grading. Iran J Dermatol. 2002;6:10-5.

Coolins GL, Nickoonahand N, Morgan MB. Changing demographics and pathology of nonmelanoma skin cancer in the last 30 years. Semin Cutan Med Surg. 2004;23:80-3.

Abedipour M. Survey of a-10 year incidence of non-melanoma skin cancer in Iran, a clinicopathological study. Acta Medica Iranica. 1995;33:96-9.

Kavoussi H, Rezaei M, Ebrahimi A, Hosseini S. Epidemiological indices of non-melanoma skin cancers in Kermanshah, Iran. J Pak Assoc. 2012;22:112-7.






Original Research Articles